Sonata and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Sonata (zaleplon), especially for people who are female, also take Zantac, and have Osteoporosis.

The phase IV clinical study analyzes which people have Cachexia when taking Sonata. It is created by eHealthMe based on reports of 3,092 people who have side effects when taking Sonata from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 666 drugs and 1,201 conditions by eHealthMe. Check the latest studies of Cachexia.

On Jun, 15, 2026

3,092 people reported to have side effects when taking Sonata.
Among them, 18 people (0.58%) have Cachexia.

Among these 18 people:

What is the gender of people who have Cachexia when taking Sonata? *

female: 100 %
male: 0.0 %

What are other drugs people take besides Sonata? *

What are other side effects people have besides Cachexia? *

Gastritis (inflammation of stomach): 18 people, 100.00%
Facial Pain: 18 people, 100.00%
Jaundice - Yellow Skin (a yellowish pigmentation of the skin): 18 people, 100.00%
Periodontal Disease (disease that attacks the gum and bone and around the teeth): 18 people, 100.00%
Pain: 18 people, 100.00%
Osteoporosis (bones weak and more likely to break): 18 people, 100.00%
Osteopenia (a condition where bone mineral density is lower than normal): 18 people, 100.00%
Osteonecrosis Of Jaw (death of bone of jaw): 18 people, 100.00%
Osteomyelitis Chronic (long lasting infection of bone marrow): 18 people, 100.00%
Hepatitis (inflammation of the liver): 18 people, 100.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 16 people, 88.89%
Sinus Disorder (disease of sinus): 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sonata:

Sonata (3,330 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (666 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,201 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon (the active ingredients of Sonata) and Sonata (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.