Sonata and Intervertebral disc degeneration - a phase IV clinical study of FDA data

Summary:

Intervertebral disc degeneration is reported as a side effect among people who take Sonata (zaleplon), especially for people who are female, 60+ old, also take Zometa, and have Osteoporosis.

The phase IV clinical study analyzes which people have Intervertebral disc degeneration when taking Sonata. It is created by eHealthMe based on reports of 3,092 people who have side effects when taking Sonata from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Intervertebral disc degeneration?

Intervertebral disc degeneration (spinal disc degeneration) is found to be associated with 1,318 drugs and 1,493 conditions by eHealthMe. Check the latest studies of Intervertebral disc degeneration.

On Jul, 09, 2026

3,092 people reported to have side effects when taking Sonata.
Among them, 37 people (1.2%) have Intervertebral disc degeneration.

Could Sonata cause Intervertebral disc degeneration?

Among these 37 people:

What is the gender of people who have Intervertebral disc degeneration when taking Sonata? *

female: 68.57 %
male: 31.43 %

What is the age of people who have Intervertebral disc degeneration when taking Sonata? *

What are other drugs people take besides Sonata? *

Zometa: 29 people, 78.38%
Prevacid: 24 people, 64.86%
Norco: 23 people, 62.16%
Amoxicillin: 21 people, 56.76%
Demerol: 21 people, 56.76%
Benadryl: 20 people, 54.05%
Zofran: 20 people, 54.05%
Zantac: 19 people, 51.35%
Diazepam: 19 people, 51.35%
Chlorhexidine Gluconate: 19 people, 51.35%

What are other side effects people have besides Intervertebral disc degeneration? *

Pain: 33 people, 89.19%
Stress And Anxiety: 33 people, 89.19%
Dyspnea (difficult or laboured breathing): 31 people, 83.78%
Intervertebral Disc Protrusion (spinal disc protrusion): 31 people, 83.78%
Osteonecrosis Of Jaw (death of bone of jaw): 29 people, 78.38%
Fall: 29 people, 78.38%
Hypoaesthesia (reduced sense of touch or sensation): 27 people, 72.97%
Depression: 25 people, 67.57%
High Blood Pressure: 25 people, 67.57%
Injury: 24 people, 64.86%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 18 people, 48.65%
Pain: 4 people, 10.81%
Multiple Myeloma (cancer of the plasma cells): 4 people, 10.81%
Breast Cancer: 3 people, 8.11%
Metastases To Bone (cancer spreads to bone): 3 people, 8.11%
Sinus Disorder (disease of sinus): 1 person, 2.70%
Heart Rate Irregular: 1 person, 2.70%
Arrhythmias (irregular heartbeat): 1 person, 2.70%
Back Pain: 1 person, 2.70%
Diabetes: 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and have Intervertebral disc degeneration?

- Check whether Intervertebral disc degeneration is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sonata:

Sonata (3,330 reports)

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,318 drugs)

Browse all the conditions that are associated with Intervertebral disc degeneration:

Intervertebral disc degeneration (1,493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon (the active ingredients of Sonata) and Sonata (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.