Sonata and Muscle strain - a phase IV clinical study of FDA data

Summary:

Muscle strain is reported as a side effect among people who take Sonata (zaleplon), especially for people who are female, 40-49 old, also take Norco, and have Osteoporosis.

The phase IV clinical study analyzes which people have Muscle strain when taking Sonata. It is created by eHealthMe based on reports of 3,092 people who have side effects when taking Sonata from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Muscle strain?

Muscle strain (an injury to a muscle in which the muscle fibres tear) is found to be associated with 919 drugs and 828 conditions by eHealthMe. Check the latest studies of Muscle strain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

3,092 people reported to have side effects when taking Sonata.
Among them, 29 people (0.94%) have Muscle strain.

Among these 29 people:

What is the gender of people who have Muscle strain when taking Sonata? *

female: 89.29 %
male: 10.71 %

What is the age of people who have Muscle strain when taking Sonata? *

What are other drugs people take besides Sonata? *

Norco: 21 people, 72.41%
Demerol: 19 people, 65.52%
Zometa: 19 people, 65.52%
Benadryl: 18 people, 62.07%
Diazepam: 18 people, 62.07%
Prevacid: 18 people, 62.07%
Amoxicillin: 17 people, 58.62%
Calcitonin Salmon: 17 people, 58.62%
Reglan: 17 people, 58.62%
Chlorhexidine Gluconate: 17 people, 58.62%

What are other side effects people have besides Muscle strain? *

Pain: 25 people, 86.21%
Fall: 24 people, 82.76%
Dyspnea (difficult or laboured breathing): 23 people, 79.31%
Intervertebral Disc Protrusion (spinal disc protrusion): 22 people, 75.86%
Stress And Anxiety: 22 people, 75.86%
Depression: 21 people, 72.41%
Vision Blurred: 21 people, 72.41%
Intervertebral Disc Degeneration (spinal disc degeneration): 21 people, 72.41%
Hypoaesthesia (reduced sense of touch or sensation): 21 people, 72.41%
Joint Swelling: 21 people, 72.41%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 15 people, 51.72%
Hepatitis C: 4 people, 13.79%
Post-Traumatic Stress Disorder: 2 people, 6.90%
Pain: 2 people, 6.90%
Stress And Anxiety: 1 person, 3.45%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.45%
Bipolar Disorder (mood disorder): 1 person, 3.45%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 3.45%
Depression: 1 person, 3.45%
Dizziness: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and have Muscle strain?

- Check whether Muscle strain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sonata:

Sonata (3,330 reports)

Muscle strain treatments and more:

Muscle strain (12,853 reports)

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle strain:

Muscle strain (919 drugs)

Browse all the conditions that are associated with Muscle strain:

Muscle strain (828 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon (the active ingredients of Sonata) and Sonata (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.