Soolantra and Application site erythema - a phase IV clinical study of FDA data

Summary:

Application site erythema is reported as a side effect among people who take Soolantra (ivermectin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Clopidogrel, and have Rosacea.

The phase IV clinical study analyzes which people have Application site erythema when taking Soolantra. It is created by eHealthMe based on reports of 1,057 people who have side effects when taking Soolantra from the FDA, and is updated regularly.

What is Soolantra?

Soolantra has active ingredients of ivermectin. eHealthMe is studying from 1,068 Soolantra users. Check the latest studies of Soolantra.

What is Application site erythema?

Application site erythema (redness of the skin at application site) is found to be associated with 670 drugs and 950 conditions by eHealthMe. Check the latest studies of Application site erythema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

1,057 people reported to have side effects when taking Soolantra.
Among them, 22 people (2.08%) have Application site erythema.

Could Soolantra cause Application site erythema?

Among these 22 people:

How long have people been on Soolantra when they have Application site erythema? *

What is the gender of people who have Application site erythema when taking Soolantra? *

female: 87.5 %
male: 12.5 %

What is the age of people who have Application site erythema when taking Soolantra? *

What are other drugs people take besides Soolantra? *

What are other side effects people have besides Application site erythema? *

Application Site Pain: 10 people, 45.45%
Application Site Swelling: 7 people, 31.82%
Application Site Dryness: 7 people, 31.82%
Rosacea (a skin condition that causes facial redness): 6 people, 27.27%
Application Site Exfoliation (application site removal of the oldest dead skin cells on the skin's outermost surface): 6 people, 27.27%
Application Site Pruritus (application site severe itching of the skin): 5 people, 22.73%
Application Site Irritation: 4 people, 18.18%
Application Site Reaction: 3 people, 13.64%
Application Site Inflammation: 3 people, 13.64%
Lip Blister: 2 people, 9.09%

What are the existing conditions these people have? *

Rosacea (a skin condition that causes facial redness): 20 people, 90.91%
Transient Acantholytic Dermatosis (a skin condition that causes the appearance of small, red spots on chest and back): 2 people, 9.09%
High Blood Cholesterol: 2 people, 9.09%
Cardiac Disorder: 2 people, 9.09%
Actinic Keratosis (skin disease due to sun exposure): 2 people, 9.09%
High Blood Pressure: 1 person, 4.55%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 4.55%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 4.55%
Conjunctivitis (pink eye): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Soolantra and have Application site erythema?

- Check whether Application site erythema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soolantra:

Soolantra (1,068 reports)

Browse all side effects of Soolantra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site erythema:

Application site erythema (670 drugs)

Browse all the conditions that are associated with Application site erythema:

Application site erythema (950 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ivermectin (the active ingredients of Soolantra) and Soolantra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.