Sovaldi and Hypoaesthesia - a phase IV clinical study of FDA data

Summary:

Hypoaesthesia is reported as a side effect among people who take Sovaldi (sofosbuvir), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Pegasys, and have Hepatitis c.

The phase IV clinical study analyzes which people have Hypoaesthesia when taking Sovaldi. It is created by eHealthMe based on reports of 12,681 people who have side effects when taking Sovaldi from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Hypoaesthesia?

Hypoaesthesia (reduced sense of touch or sensation) is found to be associated with 2,944 drugs and 3,180 conditions by eHealthMe. Check the latest studies of Hypoaesthesia.

On Jan, 08, 2026

12,681 people reported to have side effects when taking Sovaldi.
Among them, 56 people (0.44%) have Hypoaesthesia.

Among these 56 people:

* Approximation only. Some reports may have incomplete information.

Do you take Sovaldi and have Hypoaesthesia?

- Check whether Hypoaesthesia is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sovaldi:

Sovaldi (12,697 reports)

Hypoaesthesia treatments and more:

Hypoaesthesia (189,312 reports)

How severe was Hypoaesthesia and when was it recovered:

Hypoaesthesia in Sovaldi

Expand to all the drugs that have ingredients of sofosbuvir:

Hypoaesthesia and drugs with ingredients of sofosbuvir

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Sovaldi side effects:

Sovaldi side effect: Nausea (feeling of having an urge to vomit) (931 reports)
Sovaldi side effect: Anaemia (lack of blood) (643 reports)

Browse all side effects of Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hypoaesthesia:

Browse all the drugs that are associated with Hypoaesthesia:

Hypoaesthesia (2,944 drugs)

Common conditions associated with Hypoaesthesia:

Multiple sclerosis aggravated: 27,611 reports
Arthritis - rheumatoid: 13,640 reports
Pain: 7,207 reports
Hypertension: 7,106 reports
Alternative medicine - pain relief: 7,100 reports
Blood pressure - high: 7,056 reports
Plasmacytoma of bone: 5,443 reports
Depression: 4,888 reports
Antidepressant therapy: 4,874 reports
Hyperlipoproteinemia: 4,481 reports

Browse all the conditions that are associated with Hypoaesthesia:

Hypoaesthesia (3,180 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir (the active ingredients of Sovaldi) and Sovaldi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.