Sovaldi and Pyrosis - a phase IV clinical study of FDA data

Summary:

Pyrosis is reported as a side effect among people who take Sovaldi (sofosbuvir), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Daklinza, and have Hepatitis c.

The phase IV clinical study analyzes which people have Pyrosis when taking Sovaldi. It is created by eHealthMe based on reports of 12,681 people who have side effects when taking Sovaldi from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Pyrosis?

Pyrosis (painful burning sensation in the chest caused by gastroesophageal reflux) is found to be associated with 3,472 drugs and 3,480 conditions by eHealthMe. Check the latest studies of Pyrosis.

On May, 11, 2026

12,681 people reported to have side effects when taking Sovaldi.
Among them, 48 people (0.38%) have Pyrosis.

Among these 48 people:

How long have people been on Sovaldi when they have Pyrosis? *

What is the gender of people who have Pyrosis when taking Sovaldi? *

female: 51.11 %
male: 48.89 %

What is the age of people who have Pyrosis when taking Sovaldi? *

What are other drugs people take besides Sovaldi? *

What are other side effects people have besides Pyrosis? *

Fatigue (feeling of tiredness): 15 people, 31.25%
Dyspnea (difficult or laboured breathing): 14 people, 29.17%
Insomnia (sleeplessness): 14 people, 29.17%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 12 people, 25.00%
Constipation: 12 people, 25.00%
Weight Decreased: 12 people, 25.00%
Eye Discharge: 11 people, 22.92%
Rashes (redness): 11 people, 22.92%
Fever: 11 people, 22.92%
Headache (pain in head): 10 people, 20.83%

What are the existing conditions these people have? *

Hepatitis C: 19 people, 39.58%
Nausea (feeling of having an urge to vomit): 7 people, 14.58%
Headache (pain in head): 7 people, 14.58%
Herpes Virus Infection: 7 people, 14.58%
Indigestion: 7 people, 14.58%
Inflammation: 7 people, 14.58%
Fatigue (feeling of tiredness): 7 people, 14.58%
Ammonia Abnormal: 7 people, 14.58%
Urticaria (rash of round, red welts on the skin that itch intensely): 6 people, 12.50%
Tropical Spastic Paresis (an incurable viral infection of the spinal cord that causes weakness in the legs): 6 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Sovaldi and have Pyrosis?

- Check whether Pyrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sovaldi:

Sovaldi (12,697 reports)

Pyrosis treatments and more:

Pyrosis (445,826 reports)

Browse all side effects of Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pyrosis:

Pyrosis (3,472 drugs)

Browse all the conditions that are associated with Pyrosis:

Pyrosis (3,480 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir (the active ingredients of Sovaldi) and Sovaldi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.