Sovaldi and Shingles - a phase IV clinical study of FDA data

Summary:

Shingles is reported as a side effect among people who take Sovaldi (sofosbuvir), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Rebetol, and have Hepatitis c.

The phase IV clinical study analyzes which people have Shingles when taking Sovaldi. It is created by eHealthMe based on reports of 12,681 people who have side effects when taking Sovaldi from the FDA, and is updated regularly.

What is Sovaldi?

Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.

What is Shingles?

Shingles (a painful, contagious rash caused by the chickenpox virus) is found to be associated with 1,935 drugs and 2,145 conditions by eHealthMe. Check the latest studies of Shingles.

On Jun, 18, 2026

12,681 people reported to have side effects when taking Sovaldi.
Among them, 14 people (0.11%) have Shingles.

Among these 14 people:

How long have people been on Sovaldi when they have Shingles? *

What is the gender of people who have Shingles when taking Sovaldi? *

female: 64.29 %
male: 35.71 %

What is the age of people who have Shingles when taking Sovaldi? *

What are other drugs people take besides Sovaldi? *

What are other side effects people have besides Shingles? *

Haemoglobin Decreased: 4 people, 28.57%
White Blood Cell Count Decreased: 3 people, 21.43%
Drowning (process of experiencing respiratory impairment from submersion/immersion in liquid): 3 people, 21.43%
Loss Of Consciousness: 3 people, 21.43%
Rashes (redness): 2 people, 14.29%
Pain: 2 people, 14.29%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 2 people, 14.29%
Infection: 2 people, 14.29%
Stress And Anxiety: 2 people, 14.29%
Renal Impairment (severely reduced kidney function): 1 person, 7.14%

What are the existing conditions these people have? *

Hepatitis C: 6 people, 42.86%
Stress And Anxiety: 1 person, 7.14%
Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
Nervousness: 1 person, 7.14%
Joint Pain: 1 person, 7.14%
Hepatitis Infectious: 1 person, 7.14%
Hepatitis (inflammation of the liver): 1 person, 7.14%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Sovaldi and have Shingles?

- Check whether Shingles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sovaldi:

Sovaldi (12,697 reports)

Shingles treatments and more:

Shingles (88,626 reports)

Browse all side effects of Sovaldi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shingles:

Shingles (1,935 drugs)

Browse all the conditions that are associated with Shingles:

Shingles (2,145 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir (the active ingredients of Sovaldi) and Sovaldi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.