Soy and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Soy (soy), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Diazepam, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Depression when taking Soy. It is created by eHealthMe based on reports of 524 people who have side effects when taking Soy from the FDA, and is updated regularly.

What is Soy?

Soy has active ingredients of soy. eHealthMe is studying from 562 Soy users. Check the latest studies of Soy.

What is Depression?

Depression is found to be associated with 3,169 drugs and 4,130 conditions by eHealthMe. Check the latest studies of Depression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

524 people reported to have side effects when taking Soy.
Among them, 11 people (2.1%) have Depression.

Among these 11 people:

How long have people been on Soy when they have Depression? *

What is the gender of people who have Depression when taking Soy? *

female: 90 %
male: 10 %

What is the age of people who have Depression when taking Soy? *

What are other drugs people take besides Soy? *

Diazepam: 3 people, 27.27%
Vytorin: 2 people, 18.18%
Seroquel: 2 people, 18.18%
Fluoxetine: 2 people, 18.18%
Carbamazepine: 2 people, 18.18%
Benicar: 2 people, 18.18%
Clonazepam: 2 people, 18.18%
Sertraline Hydrochloride: 2 people, 18.18%
Synthroid: 2 people, 18.18%
Amlodipine: 1 person, 9.09%

What are other side effects people have besides Depression? *

Weight Decreased: 3 people, 27.27%
High Blood Cholesterol: 3 people, 27.27%
Fatigue (feeling of tiredness): 3 people, 27.27%
Drug Ineffective: 2 people, 18.18%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 2 people, 18.18%
Weakness: 2 people, 18.18%
Acute Myocardial Infarction (acute heart attack): 2 people, 18.18%
Oedema Peripheral (superficial swelling): 2 people, 18.18%
Gingival Disorder (gum disease): 2 people, 18.18%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 18.18%

What are the existing conditions these people have? *

Arterial Spasm (temporary, sudden narrowing of one of the coronary arteries): 2 people, 18.18%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 18.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
Type 2 Diabetes: 1 person, 9.09%
Dysmenorrhea (painful menstruation): 1 person, 9.09%
Aplastic Anemia: 1 person, 9.09%
Back Pain: 1 person, 9.09%
Bone Disorder: 1 person, 9.09%
Bone Marrow Conditioning Regimen: 1 person, 9.09%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Soy and have Depression?

- Check whether Depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Soy:

Soy (562 reports)

Depression treatments and more:

Depression (652,162 reports)

Browse all side effects of Soy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Depression (3,169 drugs)

Browse all the conditions that are associated with Depression:

Depression (4,130 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on soy (the active ingredients of Soy) and Soy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.