Spinraza and Arthropathy - a phase IV clinical study of FDA data

Summary:

Arthropathy is reported as a side effect among people who take Spinraza (nusinersen sodium), especially for people who are male, 40-49 old, also take Evrysdi, and have Spinal muscular atrophy.

The phase IV clinical study analyzes which people have Arthropathy when taking Spinraza. It is created by eHealthMe based on reports of 7,063 people who have side effects when taking Spinraza from the FDA, and is updated regularly.

What is Spinraza?

Spinraza has active ingredients of nusinersen sodium. eHealthMe is studying from 7,063 Spinraza users. Check the latest studies of Spinraza.

What is Arthropathy?

Arthropathy is found to be associated with 1,598 drugs and 1,686 conditions by eHealthMe. Check the latest studies of Arthropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

7,063 people reported to have side effects when taking Spinraza.
Among them, 11 people (0.16%) have Arthropathy.

Among these 11 people:

What is the gender of people who have Arthropathy when taking Spinraza? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Arthropathy when taking Spinraza? *

What are other drugs people take besides Spinraza? *

Evrysdi: 1 person, 9.09%

What are other side effects people have besides Arthropathy? *

Protein Total Increased: 4 people, 36.36%
Ankle Fracture: 3 people, 27.27%
Foot Fracture: 3 people, 27.27%
Fall: 3 people, 27.27%
Lower Limb Fracture: 3 people, 27.27%
High Blood Cholesterol: 2 people, 18.18%
Procedural Pain: 2 people, 18.18%
Joint Pain: 2 people, 18.18%
General Physical Health Deterioration (weak health status): 1 person, 9.09%
Gait Disturbance: 1 person, 9.09%

What are the existing conditions these people have? *

Spinal Muscular Atrophy (wasting of spinal muscles): 10 people, 90.91%

* Approximation only. Some reports may have incomplete information.

Do you take Spinraza and have Arthropathy?

- Check whether Arthropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spinraza:

Spinraza (7,063 reports)

Arthropathy treatments and more:

Arthropathy (75,984 reports)

Browse all side effects of Spinraza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthropathy:

Arthropathy (1,598 drugs)

Browse all the conditions that are associated with Arthropathy:

Arthropathy (1,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nusinersen sodium (the active ingredients of Spinraza) and Spinraza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.