Spiriva and Adhesion - a phase IV clinical study of FDA data

Summary:

Adhesion is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are female, 60+ old, also take Advair Diskus 100/50, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Adhesion when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Adhesion?

Adhesion is found to be associated with 342 drugs and 623 conditions by eHealthMe. Check the latest studies of Adhesion.



On Nov, 22, 2025

155,418 people reported to have side effects when taking Spiriva.
Among them, 10 people (0.01%) have Adhesion.

Could Spiriva cause Adhesion?

Among these 10 people:

What is the gender of people who have Adhesion when taking Spiriva? *

  • female: 60 %
  • male: 40 %

What is the age of people who have Adhesion when taking Spiriva? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Spiriva? *

  1. Advair Diskus 100/50: 4 people, 40.00%
  2. Xanax: 3 people, 30.00%
  3. Ambien: 3 people, 30.00%
  4. Synthroid: 3 people, 30.00%
  5. Triamcinolone Acetonide: 2 people, 20.00%
  6. Percocet: 2 people, 20.00%
  7. Nexium: 2 people, 20.00%
  8. Combivent: 2 people, 20.00%
  9. Prevacid: 2 people, 20.00%
  10. Celebrex: 2 people, 20.00%

What are other side effects people have besides Adhesion? *

  1. Back Pain: 3 people, 30.00%
  2. High Blood Pressure: 3 people, 30.00%
  3. Dyspnea (difficult or laboured breathing): 3 people, 30.00%
  4. Intestinal Obstruction: 3 people, 30.00%
  5. Insomnia (sleeplessness): 3 people, 30.00%
  6. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 20.00%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 20.00%
  8. Diarrhea: 2 people, 20.00%
  9. Chest Pain: 2 people, 20.00%
  10. Irritable Bowel Syndrome: 2 people, 20.00%

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 20.00%
  2. Seasonal Allergy (allergic condition due to certain season): 1 person, 10.00%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 10.00%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 10.00%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 10.00%
  6. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 10.00%
  7. Colitis (inflammation of colon): 1 person, 10.00%
  8. Colonoscopy Abnormal: 1 person, 10.00%
  9. Constipation: 1 person, 10.00%
  10. High Blood Cholesterol: 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Adhesion?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Adhesion treatments and more:

How severe was Adhesion and when was it recovered:

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adhesion:

Browse all the conditions that are associated with Adhesion:

Drugs similar to Spiriva and Adhesion :


How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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