Spiriva and Appendicitis - a phase IV clinical study of FDA data

Summary:

Appendicitis is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Singulair, and have High blood pressure.

The phase IV clinical study analyzes which people have Appendicitis when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Appendicitis?

Appendicitis (inflammation of the appendix) is found to be associated with 859 drugs and 878 conditions by eHealthMe. Check the latest studies of Appendicitis.

On Dec, 29, 2025

155,418 people reported to have side effects when taking Spiriva.
Among them, 68 people (0.04%) have Appendicitis.

Among these 68 people:

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Appendicitis?

- Check whether Appendicitis is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Spiriva (156,666 reports)

Appendicitis treatments and more:

Appendicitis (11,953 reports)

How severe was Appendicitis and when was it recovered:

Appendicitis in Spiriva

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Appendicitis and drugs with ingredients of tiotropium bromide monohydrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Spiriva side effects:

Spiriva side effect: Dyspnea (difficult or laboured breathing) (28,968 reports)
Spiriva side effect: Asthma (14,427 reports)

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Appendicitis:

Browse all the drugs that are associated with Appendicitis:

Appendicitis (859 drugs)

Common conditions associated with Appendicitis:

Ms: 799 reports
Ra: 701 reports
Crohn's disease aggravated: 537 reports
Anxiety: 517 reports
Diabetes mellitus: 502 reports
Constipation: 497 reports
Lack of regular bowel movements: 493 reports
Dyslipidemia: 489 reports
Sleep disorder due to general medical condition, insomnia type: 447 reports
Thrombosis: 442 reports

Browse all the conditions that are associated with Appendicitis:

Appendicitis (878 conditions)

Drugs similar to Spiriva and Appendicitis :

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.