Spiriva and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Albuterol, and have Osteoporosis.

The phase IV clinical study analyzes which people have Cachexia when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 695 drugs and 1,198 conditions by eHealthMe. Check the latest studies of Cachexia.

On Mar, 18, 2026

155,418 people reported to have side effects when taking Spiriva.
Among them, 41 people (0.03%) have Cachexia.

Among these 41 people:

How long have people been on Spiriva when they have Cachexia? *

What is the gender of people who have Cachexia when taking Spiriva? *

female: 47.5 %
male: 52.5 %

What is the age of people who have Cachexia when taking Spiriva? *

What are other drugs people take besides Spiriva? *

What are other side effects people have besides Cachexia? *

Weakness: 11 people, 26.83%
Weight Decreased: 10 people, 24.39%
Fatigue (feeling of tiredness): 10 people, 24.39%
Nausea (feeling of having an urge to vomit): 8 people, 19.51%
Thrombocytopenia (decrease of platelets in blood): 8 people, 19.51%
Diarrhea: 7 people, 17.07%
Dizziness: 7 people, 17.07%
Hypotension (abnormally low blood pressure): 7 people, 17.07%
Pleural Effusion (water on the lungs): 7 people, 17.07%
Arrhythmias (irregular heartbeat): 7 people, 17.07%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 9.76%
Stress And Anxiety: 3 people, 7.32%
Cardiac Failure Congestive: 3 people, 7.32%
Depression: 3 people, 7.32%
Pain: 3 people, 7.32%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 4.88%
Bladder Cancer: 2 people, 4.88%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 2 people, 4.88%
Dyspnea (difficult or laboured breathing): 2 people, 4.88%
Hypokalemia (low potassium): 2 people, 4.88%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Spiriva (156,666 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

How severe was Cachexia and when was it recovered:

Cachexia in Spiriva

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Cachexia and drugs with ingredients of tiotropium bromide monohydrate (36 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (695 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,198 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.