Spiriva and Pco2 decreased - a phase IV clinical study of FDA data

Summary:

Pco2 decreased is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are male, 60+ old, also take Singulair, and have Hypersensitivity.

The phase IV clinical study analyzes which people have Pco2 decreased when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Pco2 decreased?

Pco2 decreased is found to be associated with 265 drugs and 460 conditions by eHealthMe. Check the latest studies of Pco2 decreased.

On Jul, 16, 2026

155,418 people reported to have side effects when taking Spiriva.
Among them, 12 people (0.01%) have Pco2 decreased.

Among these 12 people:

What is the gender of people who have Pco2 decreased when taking Spiriva? *

female: 50 %
male: 50 %

What is the age of people who have Pco2 decreased when taking Spiriva? *

What are other drugs people take besides Spiriva? *

Singulair: 7 people, 58.33%
Clorazepate Dipotassium: 4 people, 33.33%
Lansoprazole: 4 people, 33.33%
Valsartan: 4 people, 33.33%
Prazepam: 4 people, 33.33%
Haloperidol: 4 people, 33.33%
Aspirin: 4 people, 33.33%
Cialis: 3 people, 25.00%
Colace: 3 people, 25.00%
Condylox: 3 people, 25.00%

What are other side effects people have besides Pco2 decreased? *

Blood Bicarbonate Decreased: 7 people, 58.33%
Po2 Increased: 7 people, 58.33%
Blood Creatinine Increased: 6 people, 50.00%
Confusion: 5 people, 41.67%
Rales (an abnormal respiratory sound characterized by fine crackles): 5 people, 41.67%
Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 41.67%
Hypotension (abnormally low blood pressure): 5 people, 41.67%
Diarrhea: 5 people, 41.67%
Acute Kidney Failure: 5 people, 41.67%
Heart Rate Increased: 4 people, 33.33%

What are the existing conditions these people have? *

Migraine (headache): 3 people, 25.00%
Hypersensitivity: 3 people, 25.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Pco2 decreased?

- Check whether Pco2 decreased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Spiriva (156,666 reports)

Pco2 decreased treatments and more:

Pco2 decreased (1,497 reports)

How severe was Pco2 decreased and when was it recovered:

Pco2 decreased in Spiriva

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Pco2 decreased and drugs with ingredients of tiotropium bromide monohydrate (15 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pco2 decreased:

Pco2 decreased (265 drugs)

Browse all the conditions that are associated with Pco2 decreased:

Pco2 decreased (460 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.