Spiriva and Sputum culture positive - a phase IV clinical study of FDA data

Summary:

Sputum culture positive is reported as a side effect among people who take Spiriva (tiotropium bromide monohydrate), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Singulair, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Sputum culture positive when taking Spiriva. It is created by eHealthMe based on reports of 155,418 people who have side effects when taking Spiriva from the FDA, and is updated regularly.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

What is Sputum culture positive?

Sputum culture positive is found to be associated with 247 drugs and 372 conditions by eHealthMe. Check the latest studies of Sputum culture positive.

On Jun, 12, 2026

155,418 people reported to have side effects when taking Spiriva.
Among them, 20 people (0.01%) have Sputum culture positive.

Could Spiriva cause Sputum culture positive?

Among these 20 people:

How long have people been on Spiriva when they have Sputum culture positive? *

What is the gender of people who have Sputum culture positive when taking Spiriva? *

female: 85 %
male: 15 %

What is the age of people who have Sputum culture positive when taking Spiriva? *

What are other drugs people take besides Spiriva? *

What are other side effects people have besides Sputum culture positive? *

Pneumonia: 13 people, 65.00%
Pulmonary Mass: 9 people, 45.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 7 people, 35.00%
High Blood Pressure: 7 people, 35.00%
Blood Count Abnormal: 7 people, 35.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 30.00%
Mycobacterium Avium Complex Infection: 6 people, 30.00%
Productive Cough: 5 people, 25.00%
Fatigue (feeling of tiredness): 5 people, 25.00%
Dyspnea (difficult or laboured breathing): 5 people, 25.00%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 3 people, 15.00%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 5.00%
Pneumonia: 1 person, 5.00%
Nausea (feeling of having an urge to vomit): 1 person, 5.00%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%
Malignant Melanoma Stage Iv (the cancer has spread to other places in the body, such as the lung, liver, brain, bone, soft tissue, or gastrointestinal (gi) tract. cancer may have spread to places in the skin far away from where it first started): 1 person, 5.00%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 5.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Spiriva and have Sputum culture positive?

- Check whether Sputum culture positive is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spiriva:

Spiriva (156,666 reports)

Sputum culture positive treatments and more:

Sputum culture positive (1,416 reports)

How severe was Sputum culture positive and when was it recovered:

Sputum culture positive in Spiriva

Expand to all the drugs that have ingredients of tiotropium bromide monohydrate:

Sputum culture positive and drugs with ingredients of tiotropium bromide monohydrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spiriva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sputum culture positive:

Sputum culture positive (247 drugs)

Browse all the conditions that are associated with Sputum culture positive:

Sputum culture positive (372 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tiotropium bromide monohydrate (the active ingredients of Spiriva) and Spiriva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.