Spravato and Rashes - a phase IV clinical study of FDA data

Summary:

Rashes is reported as a side effect among people who take Spravato (esketamine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lamictal, and have Depression.

The phase IV clinical study analyzes which people have Rashes when taking Spravato. It is created by eHealthMe based on reports of 7,912 people who have side effects when taking Spravato from the FDA, and is updated regularly.

What is Spravato?

Spravato has active ingredients of esketamine hydrochloride. eHealthMe is studying from 7,920 Spravato users. Check the latest studies of Spravato.

What is Rashes?

Rashes (redness) is found to be associated with 3,713 drugs and 6,213 conditions by eHealthMe. Check the latest studies of Rashes.

On Jul, 29, 2026

7,912 people reported to have side effects when taking Spravato.
Among them, 31 people (0.39%) have Rashes.

Among these 31 people:

How long have people been on Spravato when they have Rashes? *

What is the gender of people who have Rashes when taking Spravato? *

female: 80 %
male: 20 %

What is the age of people who have Rashes when taking Spravato? *

What are other drugs people take besides Spravato? *

What are other side effects people have besides Rashes? *

Dissociation: 7 people, 22.58%
Dizziness: 6 people, 19.35%
Sedation: 5 people, 16.13%
High Blood Pressure: 4 people, 12.90%
Nausea (feeling of having an urge to vomit): 4 people, 12.90%
Feeling Abnormal: 3 people, 9.68%
Sensory Disturbance (sense disturbance): 3 people, 9.68%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 9.68%
Stress And Anxiety: 3 people, 9.68%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 9.68%

What are the existing conditions these people have? *

Depression: 15 people, 48.39%
Stomatitis (inflammation of mucous membrane of mouth): 2 people, 6.45%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 6.45%
Stress And Anxiety: 1 person, 3.23%
Sleep Disorder: 1 person, 3.23%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 1 person, 3.23%
Insomnia (sleeplessness): 1 person, 3.23%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.23%
Crying: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Spravato and have Rashes?

- Check whether Rashes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Spravato:

Spravato (7,920 reports)

Rashes treatments and more:

Rashes (702,909 reports)

Browse all side effects of Spravato:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rashes:

Rashes (3,713 drugs)

Browse all the conditions that are associated with Rashes:

Rashes (6,213 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on esketamine hydrochloride (the active ingredients of Spravato) and Spravato (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.