Sprintec and Flushing - a phase IV clinical study of FDA data

Summary:

Flushing is reported as a side effect among people who take Sprintec (ethinyl estradiol; norgestimate), especially for people who are female, 30-39 old, have been taking the drug for 6 - 12 months also take Tecfidera, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Flushing when taking Sprintec. It is created by eHealthMe based on reports of 3,556 people who have side effects when taking Sprintec from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Flushing?

Flushing (the warm, red condition of human skin) is found to be associated with 2,045 drugs and 2,901 conditions by eHealthMe. Check the latest studies of Flushing.

On Oct, 27, 2025

3,556 people reported to have side effects when taking Sprintec.
Among them, 44 people (1.24%) have Flushing.

Among these 44 people:

How long have people been on Sprintec when they have Flushing? *

What is the gender of people who have Flushing when taking Sprintec? *

female: 97.62 %
male: 2.38 %

What is the age of people who have Flushing when taking Sprintec? *

What are other drugs people take besides Sprintec? *

What are other side effects people have besides Flushing? *

Fatigue (feeling of tiredness): 10 people, 22.73%
Nausea (feeling of having an urge to vomit): 8 people, 18.18%
Headache (pain in head): 7 people, 15.91%
Stress And Anxiety: 7 people, 15.91%
Diarrhea: 6 people, 13.64%
Dizziness: 5 people, 11.36%
Weakness: 5 people, 11.36%
Rashes (redness): 5 people, 11.36%
Depression: 5 people, 11.36%
Dyspnea (difficult or laboured breathing): 5 people, 11.36%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 25 people, 56.82%
Gait Apraxia: 4 people, 9.09%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 6.82%
Depression: 3 people, 6.82%
Stress And Anxiety: 3 people, 6.82%
Gait Disturbance: 2 people, 4.55%
Muscle Spasms (muscle contraction): 2 people, 4.55%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 4.55%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.55%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Sprintec and have Flushing?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sprintec:

Sprintec (4,397 reports)

Flushing treatments and more:

Flushing (117,675 reports)

How severe was Flushing and when was it recovered:

Flushing in Sprintec

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Flushing and drugs with ingredients of ethinyl estradiol; norgestimate (130 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sprintec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flushing:

Flushing (2,045 drugs)

Browse all the conditions that are associated with Flushing:

Flushing (2,901 conditions)

Drugs similar to Sprintec and Flushing :

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Sprintec) and Sprintec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.