Sprintec and Heavy or prolong menstrual bleeding - a phase IV clinical study of FDA data

Summary:

Heavy or prolong menstrual bleeding is reported as a side effect among people who take Sprintec (ethinyl estradiol; norgestimate), especially for people who are 20-29 old, have been taking the drug for 1 - 6 months also take Mirena, and have Pain.

The phase IV clinical study analyzes which people have Heavy or prolong menstrual bleeding when taking Sprintec. It is created by eHealthMe based on reports of 3,556 people who have side effects when taking Sprintec from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Heavy or prolong menstrual bleeding?

Heavy or prolong menstrual bleeding is found to be associated with 745 drugs and 1,264 conditions by eHealthMe. Check the latest studies of Heavy or prolong menstrual bleeding.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

3,556 people reported to have side effects when taking Sprintec.
Among them, 56 people (1.57%) have Heavy or prolong menstrual bleeding.

Could Sprintec cause Heavy or prolong menstrual bleeding?

Among these 56 people:

How long have people been on Sprintec when they have Heavy or prolong menstrual bleeding? *

What is the age of people who have Heavy or prolong menstrual bleeding when taking Sprintec? *

What are other drugs people take besides Sprintec? *

What are other side effects people have besides Heavy or prolong menstrual bleeding? *

Dysmenorrhea (painful menstruation): 9 people, 16.07%
Pain: 8 people, 14.29%
Drug Ineffective: 7 people, 12.50%
Nausea (feeling of having an urge to vomit): 7 people, 12.50%
Abdominal Pain: 7 people, 12.50%
Muscle Spasms (muscle contraction): 7 people, 12.50%
Injury: 6 people, 10.71%
Fatigue (feeling of tiredness): 6 people, 10.71%
Uterine Perforation (accidental puncture of the uterus): 6 people, 10.71%
Stress And Anxiety: 5 people, 8.93%

What are the existing conditions these people have? *

Pain: 7 people, 12.50%
Depression: 4 people, 7.14%
Migraine Without Aura (headache without neurological problems): 3 people, 5.36%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 5.36%
Insomnia (sleeplessness): 3 people, 5.36%
Menstruation Irregular: 3 people, 5.36%
Stress And Anxiety: 3 people, 5.36%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.36%
Nausea (feeling of having an urge to vomit): 2 people, 3.57%
Ovarian Cysts (fluid filled sacs of the ovary): 2 people, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Sprintec and have Heavy or prolong menstrual bleeding?

- Check whether Heavy or prolong menstrual bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sprintec:

Sprintec (4,397 reports)

Heavy or prolong menstrual bleeding treatments and more:

Heavy or prolong menstrual bleeding (38,063 reports)

How severe was Heavy or prolong menstrual bleeding and when was it recovered:

Heavy or prolong menstrual bleeding in Sprintec

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Heavy or prolong menstrual bleeding and drugs with ingredients of ethinyl estradiol; norgestimate (271 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sprintec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heavy or prolong menstrual bleeding:

Heavy or prolong menstrual bleeding (745 drugs)

Browse all the conditions that are associated with Heavy or prolong menstrual bleeding:

Heavy or prolong menstrual bleeding (1,264 conditions)

Related publications that referenced our studies

Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Sprintec) and Sprintec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.