Sprintec and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Sprintec (ethinyl estradiol; norgestimate), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Humira, and have Narcolepsy.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Sprintec. It is created by eHealthMe based on reports of 3,556 people who have side effects when taking Sprintec from the FDA, and is updated regularly.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,200 drugs and 1,700 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

On Nov, 18, 2025

3,556 people reported to have side effects when taking Sprintec.
Among them, 20 people (0.56%) have Peripheral swelling.

Could Sprintec cause Peripheral swelling?

Among these 20 people:

How long have people been on Sprintec when they have Peripheral swelling? *

What is the gender of people who have Peripheral swelling when taking Sprintec? *

female: 100 %
male: 0.0 %

What is the age of people who have Peripheral swelling when taking Sprintec? *

What are other drugs people take besides Sprintec? *

What are other side effects people have besides Peripheral swelling? *

Joint Swelling: 4 people, 20.00%
Pain: 4 people, 20.00%
Pain In Extremity: 4 people, 20.00%
Gait Disturbance: 3 people, 15.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 15.00%
Dyspnea (difficult or laboured breathing): 3 people, 15.00%
Swelling Face: 3 people, 15.00%
Nausea (feeling of having an urge to vomit): 3 people, 15.00%
Joint Pain: 3 people, 15.00%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 15.00%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 25.00%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 15.00%
Pain: 3 people, 15.00%
Depression: 2 people, 10.00%
Headache (pain in head): 2 people, 10.00%
Stress And Anxiety: 2 people, 10.00%
Uveitis (inflammation of the uvea): 2 people, 10.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
Neuralgia (pain in one or more nerves): 1 person, 5.00%
Nuclear Magnetic Resonance Imaging Brain: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sprintec and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sprintec:

Sprintec (4,397 reports)

Peripheral swelling treatments and more:

Peripheral swelling (168,738 reports)

How severe was Peripheral swelling and when was it recovered:

Peripheral swelling in Sprintec

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Peripheral swelling and drugs with ingredients of ethinyl estradiol; norgestimate (14 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sprintec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,200 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,700 conditions)

Drugs similar to Sprintec and Peripheral swelling :

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Sprintec) and Sprintec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.