Sprix and Nausea aggravated - a phase IV clinical study of FDA data

Summary:

Nausea aggravated is reported as a side effect among people who take Sprix (ketorolac tromethamine), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Fish Oil, and have Migraine.

The phase IV clinical study analyzes which people have Nausea aggravated when taking Sprix. It is created by eHealthMe based on reports of 610 people who have side effects when taking Sprix from the FDA, and is updated regularly.

What is Sprix?

Sprix has active ingredients of ketorolac tromethamine. eHealthMe is studying from 616 Sprix users. Check the latest studies of Sprix.

What is Nausea aggravated?

Nausea aggravated (an urge to vomit) is found to be associated with 3,429 drugs and 1,085 conditions by eHealthMe. Check the latest studies of Nausea aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

610 people reported to have side effects when taking Sprix.
Among them, 21 people (3.44%) have Nausea aggravated.

Could Sprix cause Nausea aggravated?

Among these 21 people:

How long have people been on Sprix when they have Nausea aggravated? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Nausea aggravated when taking Sprix? *

  • female: 91.67 %
  • male: 8.33 %

What is the age of people who have Nausea aggravated when taking Sprix? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 45.45 %
  • 40-49: 27.27 %
  • 50-59: 18.18 %
  • 60+: 9.09 %

What are other drugs people take besides Sprix? *

  1. Fish Oil: 5 people, 23.81%
  2. Vitamin D3: 4 people, 19.05%
  3. Tylenol: 3 people, 14.29%
  4. Requip: 3 people, 14.29%
  5. Cambia: 3 people, 14.29%
  6. Vitamin C: 3 people, 14.29%
  7. Zofran: 3 people, 14.29%
  8. Proair Hfa: 3 people, 14.29%
  9. Benadryl: 2 people, 9.52%
  10. Botox: 2 people, 9.52%

What are other side effects people have besides Nausea aggravated? *

  1. Nausea And Vomiting: 6 people, 28.57%
  2. Migraine (headache): 5 people, 23.81%
  3. Headache (pain in head): 4 people, 19.05%
  4. Diarrhea: 4 people, 19.05%
  5. Dizziness: 4 people, 19.05%
  6. Abdominal Pain Upper: 2 people, 9.52%
  7. Haemoglobin Increased: 2 people, 9.52%
  8. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 9.52%
  9. Hypoaesthesia (reduced sense of touch or sensation): 2 people, 9.52%
  10. Indigestion: 2 people, 9.52%

What are the existing conditions these people have? *

  1. Migraine (headache): 8 people, 38.10%
  2. Pain: 4 people, 19.05%
  3. Type 2 Diabetes: 2 people, 9.52%
  4. Procedural Pain: 2 people, 9.52%
  5. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 9.52%
  6. Neck Pain: 2 people, 9.52%
  7. Headache (pain in head): 2 people, 9.52%
  8. Depression: 2 people, 9.52%
  9. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 4.76%
  10. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Sprix and have Nausea aggravated?

- Check whether Nausea aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sprix:

Nausea aggravated treatments and more:

How severe was Nausea aggravated and when was it recovered:

Expand to all the drugs that have ingredients of ketorolac tromethamine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sprix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea aggravated:

Browse all the conditions that are associated with Nausea aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on ketorolac tromethamine (the active ingredients of Sprix) and Sprix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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