Starlix and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Starlix (nateglinide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lantus, and have Metastases to bone.

The phase IV clinical study analyzes which people have Oedema when taking Starlix. It is created by eHealthMe based on reports of 3,726 people who have side effects when taking Starlix from the FDA, and is updated regularly.

What is Starlix?

Starlix has active ingredients of nateglinide. It is often used in diabetes. eHealthMe is studying from 3,768 Starlix users. Check the latest studies of Starlix.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,158 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

3,726 people reported to have side effects when taking Starlix.
Among them, 41 people (1.1%) have Oedema.

Among these 41 people:

How long have people been on Starlix when they have Oedema? *

What is the gender of people who have Oedema when taking Starlix? *

female: 45.71 %
male: 54.29 %

What is the age of people who have Oedema when taking Starlix? *

What are other drugs people take besides Starlix? *

What are other side effects people have besides Oedema? *

Pain: 23 people, 56.10%
Enlarged Heart: 18 people, 43.90%
Hypotension (abnormally low blood pressure): 17 people, 41.46%
Anaemia (lack of blood): 17 people, 41.46%
Dyspnea (difficult or laboured breathing): 17 people, 41.46%
Oesophagitis (inflammation of oesophagus): 17 people, 41.46%
Constipation: 17 people, 41.46%
Sepsis (a severe blood infection that can lead to organ failure and death): 17 people, 41.46%
Confusional State: 16 people, 39.02%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 16 people, 39.02%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 12 people, 29.27%
High Blood Pressure: 11 people, 26.83%
Depression: 11 people, 26.83%
Breast Cancer: 11 people, 26.83%
Bone Pain: 11 people, 26.83%
Bone Density Decreased: 4 people, 9.76%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 2.44%
Nuclear Magnetic Resonance Imaging Brain: 1 person, 2.44%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 1 person, 2.44%
Heart Disease: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Starlix and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Starlix:

Starlix (3,768 reports)

Oedema treatments and more:

Oedema (78,747 reports)

Browse all side effects of Starlix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Oedema (2,158 drugs)

Browse all the conditions that are associated with Oedema:

Oedema (2,311 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nateglinide (the active ingredients of Starlix) and Starlix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.