Stelara and Aseptic necrosis - a phase IV clinical study of FDA data

Summary:

Aseptic necrosis is reported as a side effect among people who take Stelara (ustekinumab), especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years also take Enbrel, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Aseptic necrosis when taking Stelara. It is created by eHealthMe based on reports of 95,658 people who have side effects when taking Stelara from the FDA, and is updated regularly.

What is Stelara?

Stelara has active ingredients of ustekinumab. It is often used in psoriasis. eHealthMe is studying from 96,053 Stelara users. Check the latest studies of Stelara.

What is Aseptic necrosis?

Aseptic necrosis (the death of bone tissue due to a lack of blood supply) is found to be associated with 1,347 drugs and 1,696 conditions by eHealthMe. Check the latest studies of Aseptic necrosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 29, 2026

95,658 people reported to have side effects when taking Stelara.
Among them, 56 people (0.06%) have Aseptic necrosis.

Among these 56 people:

How long have people been on Stelara when they have Aseptic necrosis? *

What is the gender of people who have Aseptic necrosis when taking Stelara? *

female: 30.77 %
male: 69.23 %

What is the age of people who have Aseptic necrosis when taking Stelara? *

What are other drugs people take besides Stelara? *

What are other side effects people have besides Aseptic necrosis? *

Drug Effect Decreased: 19 people, 33.93%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 17.86%
Volvulus (obstruction caused by twisting of the stomach or intestine): 10 people, 17.86%
Sepsis (a severe blood infection that can lead to organ failure and death): 10 people, 17.86%
Drug Ineffective: 9 people, 16.07%
Intestinal Obstruction: 9 people, 16.07%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 16.07%
Migraine (headache): 7 people, 12.50%
Asthma: 7 people, 12.50%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 6 people, 10.71%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 21.43%
Joint Pain: 5 people, 8.93%
Muscle Aches (muscle pain): 5 people, 8.93%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 5.36%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.36%
Inflammatory Bowel Disease: 2 people, 3.57%
Oesophagitis (inflammation of oesophagus): 1 person, 1.79%
Hyperchlorhydria (gastric acid levels are higher in stomach): 1 person, 1.79%
Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 1 person, 1.79%
Birth Control: 1 person, 1.79%

* Approximation only. Some reports may have incomplete information.

Do you take Stelara and have Aseptic necrosis?

- Check whether Aseptic necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Stelara:

Stelara (96,053 reports)

Aseptic necrosis treatments and more:

Aseptic necrosis (59,829 reports)

Browse all side effects of Stelara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aseptic necrosis:

Aseptic necrosis (1,347 drugs)

Browse all the conditions that are associated with Aseptic necrosis:

Aseptic necrosis (1,696 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ustekinumab (the active ingredients of Stelara) and Stelara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.