Stelara and Fluid retention - a phase IV clinical study of FDA data

Summary:

Fluid retention is reported as a side effect among people who take Stelara (ustekinumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Otezla, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Fluid retention when taking Stelara. It is created by eHealthMe based on reports of 95,658 people who have side effects when taking Stelara from the FDA, and is updated regularly.

What is Stelara?

Stelara has active ingredients of ustekinumab. It is often used in psoriasis. eHealthMe is studying from 96,053 Stelara users. Check the latest studies of Stelara.

What is Fluid retention?

Fluid retention (an abnormal accumulation of fluid in the blood) is found to be associated with 1,702 drugs and 2,443 conditions by eHealthMe. Check the latest studies of Fluid retention.

On Jul, 14, 2026

95,658 people reported to have side effects when taking Stelara.
Among them, 79 people (0.08%) have Fluid retention.

Among these 79 people:

How long have people been on Stelara when they have Fluid retention? *

What is the gender of people who have Fluid retention when taking Stelara? *

female: 71.62 %
male: 28.38 %

What is the age of people who have Fluid retention when taking Stelara? *

What are other drugs people take besides Stelara? *

What are other side effects people have besides Fluid retention? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 29 people, 36.71%
Weight Increased: 27 people, 34.18%
High Blood Pressure: 24 people, 30.38%
Peripheral Swelling: 23 people, 29.11%
Pain: 22 people, 27.85%
Lower Respiratory Tract Infection: 22 people, 27.85%
Nasopharyngitis (inflammation of the nasopharynx): 22 people, 27.85%
Dyspnea (difficult or laboured breathing): 21 people, 26.58%
Malaise (a feeling of general discomfort or uneasiness): 20 people, 25.32%
Fatigue (feeling of tiredness): 20 people, 25.32%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 28 people, 35.44%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 22.78%
Ankylosing Spondylitis (type of arthritis affecting the spine): 17 people, 21.52%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 15 people, 18.99%
Stress And Anxiety: 3 people, 3.80%
Arthropathy: 3 people, 3.80%
Anaemia (lack of blood): 2 people, 2.53%
Type 2 Diabetes: 1 person, 1.27%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 1.27%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 1.27%

* Approximation only. Some reports may have incomplete information.

Do you take Stelara and have Fluid retention?

- Check whether Fluid retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Stelara:

Stelara (96,053 reports)

Fluid retention treatments and more:

Fluid retention (79,660 reports)

Browse all side effects of Stelara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fluid retention:

Fluid retention (1,702 drugs)

Browse all the conditions that are associated with Fluid retention:

Fluid retention (2,443 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ustekinumab (the active ingredients of Stelara) and Stelara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.