Stiolto respimat and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Stiolto respimat (olodaterol hydrochloride; tiotropium bromide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vitamin D3, and have Chronic obstructive pulmonary disease.

The phase IV clinical study analyzes which people have Joint swelling when taking Stiolto respimat. It is created by eHealthMe based on reports of 4,394 people who have side effects when taking Stiolto respimat from the FDA, and is updated regularly.

What is Stiolto respimat?

Stiolto respimat has active ingredients of olodaterol hydrochloride; tiotropium bromide. eHealthMe is studying from 4,438 Stiolto respimat users. Check the latest studies of Stiolto respimat.

What is Joint swelling?

Joint swelling is found to be associated with 2,121 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.



On Jul, 12, 2026

4,394 people reported to have side effects when taking Stiolto respimat.
Among them, 25 people (0.57%) have Joint swelling.

Could Stiolto respimat cause Joint swelling?

Among these 25 people:

How long have people been on Stiolto respimat when they have Joint swelling? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint swelling when taking Stiolto respimat? *

  • female: 76 %
  • male: 24 %

What is the age of people who have Joint swelling when taking Stiolto respimat? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 83.33 %

What are other drugs people take besides Stiolto respimat? *

  1. Aspirin: 5 people, 20.00%
  2. Losartan: 5 people, 20.00%
  3. Vitamin D3: 5 people, 20.00%
  4. Penicillin: 4 people, 16.00%
  5. Humira: 4 people, 16.00%
  6. Symbicort: 3 people, 12.00%
  7. Acetaminophen: 3 people, 12.00%
  8. Lasix: 2 people, 8.00%
  9. Lisinopril: 2 people, 8.00%
  10. Ipratropium Bromide: 2 people, 8.00%

What are other side effects people have besides Joint swelling? *

  1. Joint Pain: 9 people, 36.00%
  2. Cataract (clouding of the lens inside the eye): 7 people, 28.00%
  3. High Blood Pressure: 6 people, 24.00%
  4. Itching: 6 people, 24.00%
  5. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 24.00%
  6. Dyspnea (difficult or laboured breathing): 5 people, 20.00%
  7. Loss Of Consciousness: 5 people, 20.00%
  8. Peripheral Swelling: 5 people, 20.00%
  9. Weakness: 5 people, 20.00%
  10. Exposure To Communicable Disease: 4 people, 16.00%

What are the existing conditions these people have? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 12 people, 48.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 20.00%
  3. Bipolar Disorder (mood disorder): 4 people, 16.00%
  4. High Blood Pressure: 3 people, 12.00%
  5. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 12.00%
  6. Lung Disorder (lung disease): 2 people, 8.00%
  7. Blood Glucose Increased: 2 people, 8.00%
  8. Diabetes: 2 people, 8.00%
  9. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 2 people, 8.00%
  10. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Stiolto respimat and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Stiolto respimat:

Joint swelling treatments and more:

How severe was Joint swelling and when was it recovered:

Expand to all the drugs that have ingredients of olodaterol hydrochloride; tiotropium bromide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Stiolto respimat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Browse all the conditions that are associated with Joint swelling:


How the study uses the data?

The study uses data from the FDA. It is based on olodaterol hydrochloride; tiotropium bromide (the active ingredients of Stiolto respimat) and Stiolto respimat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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