Strattera and Musculoskeletal stiffness - a phase IV clinical study of FDA data

Summary:

Musculoskeletal stiffness is reported as a side effect among people who take Strattera (atomoxetine hydrochloride), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Wellbutrin, and have Systemic lupus erythematosus.

The phase IV clinical study analyzes which people have Musculoskeletal stiffness when taking Strattera. It is created by eHealthMe based on reports of 27,428 people who have side effects when taking Strattera from the FDA, and is updated regularly.

What is Strattera?

Strattera has active ingredients of atomoxetine hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,324 Strattera users. Check the latest studies of Strattera.

What is Musculoskeletal stiffness?

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves) is found to be associated with 1,956 drugs and 1,917 conditions by eHealthMe. Check the latest studies of Musculoskeletal stiffness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

27,428 people reported to have side effects when taking Strattera.
Among them, 81 people (0.3%) have Musculoskeletal stiffness.

Could Strattera cause Musculoskeletal stiffness?

Among these 81 people:

How long have people been on Strattera when they have Musculoskeletal stiffness? *

What is the gender of people who have Musculoskeletal stiffness when taking Strattera? *

female: 48.1 %
male: 51.9 %

What is the age of people who have Musculoskeletal stiffness when taking Strattera? *

What are other drugs people take besides Strattera? *

What are other side effects people have besides Musculoskeletal stiffness? *

Headache (pain in head): 33 people, 40.74%
Nausea (feeling of having an urge to vomit): 31 people, 38.27%
Fatigue (feeling of tiredness): 26 people, 32.10%
Stress And Anxiety: 25 people, 30.86%
Drowsiness: 22 people, 27.16%
Joint Pain: 21 people, 25.93%
Rashes (redness): 20 people, 24.69%
Nausea And Vomiting: 20 people, 24.69%
Weakness: 18 people, 22.22%
Tremor (trembling or shaking movements in one or more parts of your body): 17 people, 20.99%

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 12.35%
Joint Pain: 9 people, 11.11%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 6.17%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 4 people, 4.94%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 3.70%
Bipolar Disorder (mood disorder): 3 people, 3.70%
Abdominal Discomfort: 2 people, 2.47%
Menopause (end of monthly cycles in women): 2 people, 2.47%
High Blood Cholesterol: 2 people, 2.47%

* Approximation only. Some reports may have incomplete information.

Do you take Strattera and have Musculoskeletal stiffness?

- Check whether Musculoskeletal stiffness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Strattera:

Strattera (29,324 reports)

Browse all side effects of Strattera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,956 drugs)

Browse all the conditions that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,917 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on atomoxetine hydrochloride (the active ingredients of Strattera) and Strattera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.