Sublimaze and Epistaxis - a phase IV clinical study of FDA data

Summary:

Epistaxis is reported as a side effect among people who take Sublimaze (fentanyl citrate), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Peridex, and have Hypercalcaemia of malignancy.

The phase IV clinical study analyzes which people have Epistaxis when taking Sublimaze. It is created by eHealthMe based on reports of 557 people who have side effects when taking Sublimaze from the FDA, and is updated regularly.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

What is Epistaxis?

Epistaxis (bleed from the nose) is found to be associated with 3,125 drugs and 3,094 conditions by eHealthMe. Check the latest studies of Epistaxis.



On Jul, 23, 2026

557 people reported to have side effects when taking Sublimaze.
Among them, 17 people (3.05%) have Epistaxis.

Could Sublimaze cause Epistaxis?

Among these 17 people:

How long have people been on Sublimaze when they have Epistaxis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Epistaxis when taking Sublimaze? *

  • female: 94.12 %
  • male: 5.88 %

What is the age of people who have Epistaxis when taking Sublimaze? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.25 %
  • 30-39: 12.5 %
  • 40-49: 0.0 %
  • 50-59: 81.25 %
  • 60+: 0.0 %

What are other drugs people take besides Sublimaze? *

  1. Narcan: 14 people, 82.35%
  2. Peridex: 14 people, 82.35%
  3. Propofol: 13 people, 76.47%
  4. Taxotere: 13 people, 76.47%
  5. Lortab: 13 people, 76.47%
  6. Navelbine: 13 people, 76.47%
  7. Effexor: 13 people, 76.47%
  8. Decadron: 13 people, 76.47%
  9. Prevacid: 13 people, 76.47%
  10. Cisplatin: 13 people, 76.47%

What are other side effects people have besides Epistaxis? *

  1. Stress And Anxiety: 15 people, 88.24%
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 15 people, 88.24%
  3. Pain: 15 people, 88.24%
  4. Injury: 14 people, 82.35%
  5. Disability: 14 people, 82.35%
  6. Hypokalemia (low potassium): 14 people, 82.35%
  7. High Blood Pressure: 14 people, 82.35%
  8. Acute Kidney Failure: 13 people, 76.47%
  9. Skin Ulcer: 13 people, 76.47%
  10. Rectal Haemorrhage (bleeding from anus): 13 people, 76.47%

What are the existing conditions these people have? *

  1. Lung Cancer - Non-Small Cell (lung cancer): 13 people, 76.47%
  2. Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 13 people, 76.47%
  3. Pain: 6 people, 35.29%
  4. Post-Traumatic Stress Disorder: 2 people, 11.76%
  5. Oral Pain: 2 people, 11.76%
  6. Bipolar Disorder (mood disorder): 2 people, 11.76%
  7. Dry Skin: 2 people, 11.76%
  8. Swelling Face: 1 person, 5.88%
  9. Histiocytosis Haematophagic: 1 person, 5.88%
  10. Amenorrhea (absence of a menstrual period in a woman of reproductive age): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Sublimaze and have Epistaxis?

- Check whether Epistaxis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sublimaze:

Epistaxis treatments and more:

How severe was Epistaxis and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl citrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sublimaze:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Epistaxis:

Browse all the conditions that are associated with Epistaxis:


How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Sublimaze) and Sublimaze (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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