Sublimaze and Headaches - a phase IV clinical study of FDA data

Summary:

Headaches is reported as a side effect among people who take Sublimaze (fentanyl citrate), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Zofran, and have Pain.

The phase IV clinical study analyzes which people have Headaches when taking Sublimaze. It is created by eHealthMe based on reports of 557 people who have side effects when taking Sublimaze from the FDA, and is updated regularly.

What is Sublimaze?

Sublimaze has active ingredients of fentanyl citrate. eHealthMe is studying from 560 Sublimaze users. Check the latest studies of Sublimaze.

What is Headaches?

Headaches is found to be associated with 3,895 drugs and 5,787 conditions by eHealthMe. Check the latest studies of Headaches.

On Jul, 14, 2026

557 people reported to have side effects when taking Sublimaze.
Among them, 19 people (3.41%) have Headaches.

Among these 19 people:

How long have people been on Sublimaze when they have Headaches? *

What is the gender of people who have Headaches when taking Sublimaze? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Headaches when taking Sublimaze? *

What are other drugs people take besides Sublimaze? *

What are other side effects people have besides Headaches? *

Diarrhea: 12 people, 63.16%
Dyspnea (difficult or laboured breathing): 10 people, 52.63%
Weight Increased: 9 people, 47.37%
Weakness: 8 people, 42.11%
Nausea (feeling of having an urge to vomit): 8 people, 42.11%
Cough: 8 people, 42.11%
Fever: 8 people, 42.11%
Urticaria (rash of round, red welts on the skin that itch intensely): 7 people, 36.84%
Fatigue (feeling of tiredness): 7 people, 36.84%
Chest Pain: 7 people, 36.84%

What are the existing conditions these people have? *

Pain: 11 people, 57.89%
Nausea (feeling of having an urge to vomit): 9 people, 47.37%
Stress And Anxiety: 9 people, 47.37%
Depression: 9 people, 47.37%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 42.11%
Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 42.11%
Constipation: 7 people, 36.84%
Pain In Extremity: 7 people, 36.84%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 36.84%
Migraine (headache): 6 people, 31.58%

* Approximation only. Some reports may have incomplete information.

Do you take Sublimaze and have Headaches?

- Check whether Headaches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sublimaze:

Sublimaze (560 reports)

Headaches treatments and more:

Headaches (756,642 reports)

Browse all side effects of Sublimaze:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headaches:

Headaches (3,895 drugs)

Browse all the conditions that are associated with Headaches:

Headaches (5,787 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Sublimaze) and Sublimaze (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.