Subutex and Panic disorder - a phase IV clinical study of FDA data

Summary:

Panic disorder is reported as a side effect among people who take Subutex (buprenorphine hydrochloride), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Suboxone, and have Depression.

The phase IV clinical study analyzes which people have Panic disorder when taking Subutex. It is created by eHealthMe based on reports of 8,309 people who have side effects when taking Subutex from the FDA, and is updated regularly.

What is Subutex?

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 8,763 Subutex users. Check the latest studies of Subutex.

What is Panic disorder?

Panic disorder is found to be associated with 1,662 drugs and 2,056 conditions by eHealthMe. Check the latest studies of Panic disorder.



On Aug, 13, 2026

8,309 people reported to have side effects when taking Subutex.
Among them, 24 people (0.29%) have Panic disorder.

Could Subutex cause Panic disorder?

Among these 24 people:

How long have people been on Subutex when they have Panic disorder? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Panic disorder when taking Subutex? *

  • female: 66.67 %
  • male: 33.33 %

What is the age of people who have Panic disorder when taking Subutex? *

  • 0-1: 4.76 %
  • 2-9: 0.0 %
  • 10-19: 4.76 %
  • 20-29: 33.33 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 23.81 %
  • 60+: 4.76 %

What are other drugs people take besides Subutex? *

  1. Suboxone: 6 people, 25.00%
  2. Xanax: 4 people, 16.67%
  3. Lexapro: 3 people, 12.50%
  4. Nexium: 3 people, 12.50%
  5. Oxycontin: 2 people, 8.33%
  6. Cymbalta: 2 people, 8.33%
  7. Hydrocodone Bitartrate And Acetaminophen: 2 people, 8.33%
  8. Norco: 2 people, 8.33%
  9. Lunesta: 2 people, 8.33%
  10. Soma: 2 people, 8.33%

What are other side effects people have besides Panic disorder? *

  1. Stress And Anxiety: 10 people, 41.67%
  2. Depression: 7 people, 29.17%
  3. Dyspnea (difficult or laboured breathing): 6 people, 25.00%
  4. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 4 people, 16.67%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 16.67%
  6. Insomnia (sleeplessness): 4 people, 16.67%
  7. Weight Decreased: 4 people, 16.67%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 16.67%
  9. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 16.67%
  10. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 4 people, 16.67%

What are the existing conditions these people have? *

  1. Intervertebral Disc Protrusion (spinal disc protrusion): 4 people, 16.67%
  2. Depression: 4 people, 16.67%
  3. Sleep Disorder: 2 people, 8.33%
  4. Drug Dependence: 2 people, 8.33%
  5. Depressive Symptom: 2 people, 8.33%
  6. Stress And Anxiety: 1 person, 4.17%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.17%
  8. Quit Smoking: 1 person, 4.17%
  9. High Blood Pressure: 1 person, 4.17%
  10. Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Subutex and have Panic disorder?

- Check whether Panic disorder is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Subutex:

Panic disorder treatments and more:

How severe was Panic disorder and when was it recovered:

Expand to all the drugs that have ingredients of buprenorphine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Subutex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic disorder:

Browse all the conditions that are associated with Panic disorder:


How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine hydrochloride (the active ingredients of Subutex) and Subutex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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