Subutex and Seizures - a phase IV clinical study of FDA data

Summary:

Seizures is reported as a side effect among people who take Subutex (buprenorphine hydrochloride), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Suboxone, and have Drug dependence.

The phase IV clinical study analyzes which people have Seizures when taking Subutex. It is created by eHealthMe based on reports of 8,309 people who have side effects when taking Subutex from the FDA, and is updated regularly.

What is Subutex?

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 8,763 Subutex users. Check the latest studies of Subutex.

What is Seizures?

Seizures (abnormal excessive or synchronous neuronal activity in the brain) is found to be associated with 2,005 drugs and 2,276 conditions by eHealthMe. Check the latest studies of Seizures.

On Jul, 05, 2026

8,309 people reported to have side effects when taking Subutex.
Among them, 39 people (0.47%) have Seizures.

Among these 39 people:

How long have people been on Subutex when they have Seizures? *

What is the gender of people who have Seizures when taking Subutex? *

female: 44.12 %
male: 55.88 %

What is the age of people who have Seizures when taking Subutex? *

What are other drugs people take besides Subutex? *

What are other side effects people have besides Seizures? *

Drug Dependence: 8 people, 20.51%
Nausea And Vomiting: 7 people, 17.95%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 6 people, 15.38%
Drowsiness: 6 people, 15.38%
Overdose: 5 people, 12.82%
Consciousness - Decreased: 5 people, 12.82%
Migraine (headache): 5 people, 12.82%
Hyperhidrosis (abnormally increased sweating): 4 people, 10.26%
Insomnia (sleeplessness): 3 people, 7.69%
Memory Loss: 3 people, 7.69%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 15.38%
Drug Dependence: 6 people, 15.38%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 12.82%
Psychotic Disorder: 4 people, 10.26%
Alcoholism (problems with alcohol): 3 people, 7.69%
Drowsiness: 2 people, 5.13%
Depression: 2 people, 5.13%
Weight Loss: 1 person, 2.56%
Toothaches (tooth pain): 1 person, 2.56%
Quit Smoking: 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Subutex and have Seizures?

- Check whether Seizures is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Subutex:

Subutex (8,763 reports)

Seizures treatments and more:

Seizures (150,179 reports)

Browse all side effects of Subutex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Seizures:

Seizures (2,005 drugs)

Browse all the conditions that are associated with Seizures:

Seizures (2,276 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine hydrochloride (the active ingredients of Subutex) and Subutex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.