Sucralfate and Hyperchlorhydria - a phase IV clinical study of FDA data

Summary:

Hyperchlorhydria is reported as a side effect among people who take Sucralfate (sucralfate), especially for people who are male, 50-59 old, also take Prevacid, and have Hepatitis c.

The phase IV clinical study analyzes which people have Hyperchlorhydria when taking Sucralfate. It is created by eHealthMe based on reports of 17,187 people who have side effects when taking Sucralfate from the FDA, and is updated regularly.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.

What is Hyperchlorhydria?

Hyperchlorhydria (gastric acid levels are higher in stomach) is found to be associated with 389 drugs and 480 conditions by eHealthMe. Check the latest studies of Hyperchlorhydria.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

17,187 people reported to have side effects when taking Sucralfate.
Among them, 14 people (0.08%) have Hyperchlorhydria.

Could Sucralfate cause Hyperchlorhydria?

Among these 14 people:

What is the gender of people who have Hyperchlorhydria when taking Sucralfate? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Hyperchlorhydria when taking Sucralfate? *

What are other drugs people take besides Sucralfate? *

What are other side effects people have besides Hyperchlorhydria? *

Drug Ineffective: 8 people, 57.14%
General Physical Health Deterioration (weak health status): 7 people, 50.00%
Headache (pain in head): 7 people, 50.00%
Irritable Bowel Syndrome: 7 people, 50.00%
Psychomotor Hyperactivity (feelings of extreme restlessness): 7 people, 50.00%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 7 people, 50.00%
Mania (a state of abnormally elevated or irritable mood): 7 people, 50.00%
Tachyphrenia (abnormally rapid mental activity): 7 people, 50.00%
Discomfort: 7 people, 50.00%
Dizziness: 7 people, 50.00%

What are the existing conditions these people have? *

Hepatitis C: 2 people, 14.29%
Muscle Spasms (muscle contraction): 1 person, 7.14%
Mania (a state of abnormally elevated or irritable mood): 1 person, 7.14%
Lung Disorder (lung disease): 1 person, 7.14%
Indigestion: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Gastritis (inflammation of stomach): 1 person, 7.14%
Gastric Disorder (disease of stomach): 1 person, 7.14%
Flatulence (flatus expelled through the anus): 1 person, 7.14%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Sucralfate and have Hyperchlorhydria?

- Check whether Hyperchlorhydria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sucralfate:

Sucralfate (17,548 reports)

Hyperchlorhydria treatments and more:

Hyperchlorhydria (52,226 reports)

Browse all side effects of Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperchlorhydria:

Hyperchlorhydria (389 drugs)

Browse all the conditions that are associated with Hyperchlorhydria:

Hyperchlorhydria (480 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sucralfate (the active ingredients of Sucralfate) and Sucralfate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.