Sular and Flushing - a phase IV clinical study of FDA data

Summary:

Flushing is reported as a side effect among people who take Sular (nisoldipine), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Niaspan, and have High density lipoprotein decreased.

The phase IV clinical study analyzes which people have Flushing when taking Sular. It is created by eHealthMe based on reports of 1,710 people who have side effects when taking Sular from the FDA, and is updated regularly.

What is Sular?

Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.

What is Flushing?

Flushing (the warm, red condition of human skin) is found to be associated with 2,048 drugs and 2,895 conditions by eHealthMe. Check the latest studies of Flushing.



On Dec, 11, 2025

1,710 people reported to have side effects when taking Sular.
Among them, 38 people (2.22%) have Flushing.

Could Sular cause Flushing?

Among these 38 people:

How long have people been on Sular when they have Flushing? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Flushing when taking Sular? *

  • female: 57.89 %
  • male: 42.11 %

What is the age of people who have Flushing when taking Sular? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 25.0 %
  • 40-49: 3.57 %
  • 50-59: 14.29 %
  • 60+: 57.14 %

What are other drugs people take besides Sular? *

  1. Niaspan: 11 people, 28.95%
  2. Lisinopril: 9 people, 23.68%
  3. Clonidine: 7 people, 18.42%
  4. Hydrochlorothiazide: 7 people, 18.42%
  5. Synthroid: 6 people, 15.79%
  6. Zoloft: 5 people, 13.16%
  7. Aspirin: 5 people, 13.16%
  8. Welchol: 5 people, 13.16%
  9. Cozaar: 5 people, 13.16%
  10. Fioricet: 5 people, 13.16%

What are other side effects people have besides Flushing? *

  1. Headache (pain in head): 16 people, 42.11%
  2. Itching: 10 people, 26.32%
  3. Dizziness: 9 people, 23.68%
  4. Fatigue (feeling of tiredness): 8 people, 21.05%
  5. Loss Of Consciousness: 7 people, 18.42%
  6. Chest Pain: 6 people, 15.79%
  7. Rashes (redness): 6 people, 15.79%
  8. Hyperhidrosis (abnormally increased sweating): 6 people, 15.79%
  9. Weakness: 5 people, 13.16%
  10. Hypotension (abnormally low blood pressure): 5 people, 13.16%

What are the existing conditions these people have? *

  1. High Density Lipoprotein Decreased: 5 people, 13.16%
  2. High Blood Cholesterol: 3 people, 7.89%
  3. Low Density Lipoprotein Increased (cholesterol increased in blood): 2 people, 5.26%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.26%
  5. Headache (pain in head): 2 people, 5.26%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.63%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.63%
  8. Iron Deficiency Anaemia: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Sular and have Flushing?

- Check whether Flushing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sular:

Flushing treatments and more:

How severe was Flushing and when was it recovered:

Expand to all the drugs that have ingredients of nisoldipine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sular:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flushing:

Browse all the conditions that are associated with Flushing:

Drugs similar to Sular and Flushing :


How the study uses the data?

The study uses data from the FDA. It is based on nisoldipine (the active ingredients of Sular) and Sular (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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