Sulfasalazine and Enterococcal infection - a phase IV clinical study of FDA data

Summary:

Enterococcal infection is reported as a side effect among people who take Sulfasalazine (sulfasalazine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Enterococcal infection when taking Sulfasalazine. It is created by eHealthMe based on reports of 95,646 people who have side effects when taking Sulfasalazine from the FDA, and is updated regularly.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.

What is Enterococcal infection?

Enterococcal infection is found to be associated with 624 drugs and 760 conditions by eHealthMe. Check the latest studies of Enterococcal infection.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

95,646 people reported to have side effects when taking Sulfasalazine.
Among them, 16 people (0.02%) have Enterococcal infection.

Could Sulfasalazine cause Enterococcal infection?

Among these 16 people:

How long have people been on Sulfasalazine when they have Enterococcal infection? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Enterococcal infection when taking Sulfasalazine? *

  • female: 43.75 %
  • male: 56.25 %

What is the age of people who have Enterococcal infection when taking Sulfasalazine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10 %
  • 30-39: 0.0 %
  • 40-49: 20 %
  • 50-59: 30 %
  • 60+: 40 %

What are other drugs people take besides Sulfasalazine? *

  1. Methotrexate: 8 people, 50.00%
  2. Prednisolone: 7 people, 43.75%
  3. Humira: 5 people, 31.25%
  4. Naproxen: 5 people, 31.25%
  5. Prednisone: 4 people, 25.00%
  6. Remicade: 3 people, 18.75%
  7. Imuran: 3 people, 18.75%
  8. Lasix: 2 people, 12.50%
  9. Enbrel: 2 people, 12.50%
  10. Levothyroxine Sodium: 2 people, 12.50%

What are other side effects people have besides Enterococcal infection? *

  1. Pneumonia: 8 people, 50.00%
  2. Klebsiella Infection: 6 people, 37.50%
  3. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 31.25%
  4. Urinary Tract Infection: 5 people, 31.25%
  5. Stress And Anxiety: 5 people, 31.25%
  6. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 5 people, 31.25%
  7. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 5 people, 31.25%
  8. Idiopathic Pulmonary Fibrosis (chronic lung disease): 5 people, 31.25%
  9. Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 31.25%
  10. Pleural Effusion (water on the lungs): 4 people, 25.00%

What are the existing conditions these people have? *

  1. Upper Respiratory Tract Infection: 1 person, 6.25%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 6.25%
  3. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 6.25%
  4. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 6.25%
  5. Pain: 1 person, 6.25%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.25%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and have Enterococcal infection?

- Check whether Enterococcal infection is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfasalazine:

Enterococcal infection treatments and more:

How severe was Enterococcal infection and when was it recovered:

Expand to all the drugs that have ingredients of sulfasalazine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sulfasalazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enterococcal infection:

Browse all the conditions that are associated with Enterococcal infection:


How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Sulfasalazine) and Sulfasalazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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