Sulfasalazine and Nerve root compression - a phase IV clinical study of FDA data

Summary:

Nerve root compression is reported as a side effect among people who take Sulfasalazine (sulfasalazine), especially for people who are female, 50-59 old, also take Humira, and have Pain.

The phase IV clinical study analyzes which people have Nerve root compression when taking Sulfasalazine. It is created by eHealthMe based on reports of 95,646 people who have side effects when taking Sulfasalazine from the FDA, and is updated regularly.

What is Sulfasalazine?

Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.

What is Nerve root compression?

Nerve root compression is found to be associated with 191 drugs and 247 conditions by eHealthMe. Check the latest studies of Nerve root compression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

95,646 people reported to have side effects when taking Sulfasalazine.
Among them, 35 people (0.04%) have Nerve root compression.

Could Sulfasalazine cause Nerve root compression?

Among these 35 people:

What is the gender of people who have Nerve root compression when taking Sulfasalazine? *

female: 91.43 %
male: 8.57 %

What is the age of people who have Nerve root compression when taking Sulfasalazine? *

What are other drugs people take besides Sulfasalazine? *

What are other side effects people have besides Nerve root compression? *

Intervertebral Disc Protrusion (spinal disc protrusion): 29 people, 82.86%
Foot Fracture: 23 people, 65.71%
Bacteriuria (presence of bacteria in urine): 23 people, 65.71%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 23 people, 65.71%
Stomatitis (inflammation of mucous membrane of mouth): 22 people, 62.86%
Mucosal Inflammation (infection of mucous membrane): 21 people, 60.00%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 18 people, 51.43%
Osteopenia (a condition where bone mineral density is lower than normal): 11 people, 31.43%
Secondary Immunodeficiency (lack of immunity due to some disease): 9 people, 25.71%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 8 people, 22.86%

What are the existing conditions these people have? *

Pain: 6 people, 17.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 11.43%
High Blood Pressure: 4 people, 11.43%
Arrhythmias (irregular heartbeat): 3 people, 8.57%
High Blood Cholesterol: 3 people, 8.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.71%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 5.71%
Diabetes: 2 people, 5.71%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 5.71%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfasalazine and have Nerve root compression?

- Check whether Nerve root compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sulfasalazine:

Sulfasalazine (96,787 reports)

Browse all side effects of Sulfasalazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nerve root compression:

Nerve root compression (191 drugs)

Browse all the conditions that are associated with Nerve root compression:

Nerve root compression (247 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sulfasalazine (the active ingredients of Sulfasalazine) and Sulfasalazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.