Sumatriptan and Ankle fracture - a phase IV clinical study of FDA data

Summary:

Ankle fracture is reported as a side effect among people who take Sumatriptan (sumatriptan succinate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Ankle fracture when taking Sumatriptan. It is created by eHealthMe based on reports of 17,179 people who have side effects when taking Sumatriptan from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Ankle fracture?

Ankle fracture is found to be associated with 1,115 drugs and 1,050 conditions by eHealthMe. Check the latest studies of Ankle fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

17,179 people reported to have side effects when taking Sumatriptan.
Among them, 30 people (0.17%) have Ankle fracture.

$Could Sumatriptan cause Ankle fracture?$

Among these 30 people:

How long have people been on Sumatriptan when they have Ankle fracture? *

What is the gender of people who have Ankle fracture when taking Sumatriptan? *

female: 93.1 %
male: 6.9 %

What is the age of people who have Ankle fracture when taking Sumatriptan? *

What are other drugs people take besides Sumatriptan? *

Xyrem: 9 people, 30.00%
Epipen: 7 people, 23.33%
Aspirin: 7 people, 23.33%
Nexium: 7 people, 23.33%
Calcium: 6 people, 20.00%
Premarin: 6 people, 20.00%
Myrbetriq: 5 people, 16.67%
Hydrocodone Bitartrate And Acetaminophen: 5 people, 16.67%
Ultram: 5 people, 16.67%
Bentyl: 5 people, 16.67%

What are other side effects people have besides Ankle fracture? *

Fall: 13 people, 43.33%
Osteoporosis (bones weak and more likely to break): 7 people, 23.33%
Fatigue (feeling of tiredness): 7 people, 23.33%
Depression: 6 people, 20.00%
Lower Limb Fracture: 5 people, 16.67%
Joint Pain: 5 people, 16.67%
Stress And Anxiety: 5 people, 16.67%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 16.67%
Dizziness: 4 people, 13.33%
Impaired Gastric Emptying: 4 people, 13.33%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 13.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 13.33%
Immunodeficiency Common Variable: 2 people, 6.67%
Thyroid Cancer: 2 people, 6.67%
Hiv Infection: 2 people, 6.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.67%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 6.67%
Depression: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and have Ankle fracture?

- Check whether Ankle fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sumatriptan:

Sumatriptan (18,159 reports)

Ankle fracture treatments and more:

Ankle fracture (20,557 reports)

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankle fracture:

Ankle fracture (1,115 drugs)

Browse all the conditions that are associated with Ankle fracture:

Ankle fracture (1,050 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Sumatriptan) and Sumatriptan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.