Sumatriptan and Initial insomnia - a phase IV clinical study of FDA data

Summary:

Initial insomnia is reported as a side effect among people who take Sumatriptan (sumatriptan succinate), especially for people who are female, 20-29 old, also take Ocrevus, and have Fever.

The phase IV clinical study analyzes which people have Initial insomnia when taking Sumatriptan. It is created by eHealthMe based on reports of 17,179 people who have side effects when taking Sumatriptan from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Initial insomnia?

Initial insomnia (feeling of inadequate or poor-quality sleep) is found to be associated with 724 drugs and 688 conditions by eHealthMe. Check the latest studies of Initial insomnia.

On Apr, 22, 2026

17,179 people reported to have side effects when taking Sumatriptan.
Among them, 26 people (0.15%) have Initial insomnia.

Could Sumatriptan cause Initial insomnia?

Among these 26 people:

What is the gender of people who have Initial insomnia when taking Sumatriptan? *

female: 100 %
male: 0.0 %

What is the age of people who have Initial insomnia when taking Sumatriptan? *

What are other drugs people take besides Sumatriptan? *

Ocrevus: 10 people, 38.46%
Acetaminophen: 8 people, 30.77%
Taltz: 6 people, 23.08%
Methotrexate: 5 people, 19.23%
Baclofen: 5 people, 19.23%
Pantoprazole: 4 people, 15.38%
Lisinopril: 3 people, 11.54%
Topamax: 3 people, 11.54%
Lamotrigine: 3 people, 11.54%
Tizanidine Hydrochloride: 3 people, 11.54%

What are other side effects people have besides Initial insomnia? *

Nausea (feeling of having an urge to vomit): 13 people, 50.00%
Fatigue (feeling of tiredness): 13 people, 50.00%
Headache (pain in head): 12 people, 46.15%
Chills (felling of cold): 10 people, 38.46%
Weakness: 8 people, 30.77%
Stress And Anxiety: 8 people, 30.77%
Fever: 8 people, 30.77%
Sinusitis (inflammation of sinus): 8 people, 30.77%
Insomnia (sleeplessness): 7 people, 26.92%
Constipation: 7 people, 26.92%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 19.23%
Fever: 5 people, 19.23%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 15.38%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 15.38%
High Blood Pressure: 3 people, 11.54%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.69%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 7.69%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 7.69%
Pain: 2 people, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and have Initial insomnia?

- Check whether Initial insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sumatriptan:

Sumatriptan (18,159 reports)

Initial insomnia treatments and more:

Initial insomnia (12,139 reports)

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Initial insomnia:

Initial insomnia (724 drugs)

Browse all the conditions that are associated with Initial insomnia:

Initial insomnia (688 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Sumatriptan) and Sumatriptan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.