Sumatriptan and Rectal prolapse - a phase IV clinical study of FDA data

Summary:

Rectal prolapse is reported as a side effect among people who take Sumatriptan (sumatriptan succinate), especially for people who are female, 30-39 old, also take Fosamax, and have Headache.

The phase IV clinical study analyzes which people have Rectal prolapse when taking Sumatriptan. It is created by eHealthMe based on reports of 17,179 people who have side effects when taking Sumatriptan from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Rectal prolapse?

Rectal prolapse (falling of rectum from normal place) is found to be associated with 309 drugs and 341 conditions by eHealthMe. Check the latest studies of Rectal prolapse.

On Jul, 07, 2026

17,179 people reported to have side effects when taking Sumatriptan.
Among them, 16 people (0.09%) have Rectal prolapse.

Could Sumatriptan cause Rectal prolapse?

Among these 16 people:

What is the gender of people who have Rectal prolapse when taking Sumatriptan? *

female: 100 %
male: 0.0 %

What is the age of people who have Rectal prolapse when taking Sumatriptan? *

What are other drugs people take besides Sumatriptan? *

Fosamax: 11 people, 68.75%
Linzess: 5 people, 31.25%
Topiramate: 4 people, 25.00%
Ergocalciferol: 4 people, 25.00%
Restasis: 4 people, 25.00%
Remeron: 3 people, 18.75%
Levetiracetam: 3 people, 18.75%
Granisetron Hydrochloride: 3 people, 18.75%
Phenytoin: 3 people, 18.75%
Potassium Chloride: 3 people, 18.75%

What are other side effects people have besides Rectal prolapse? *

High Blood Pressure: 9 people, 56.25%
High Blood Cholesterol: 9 people, 56.25%
Gout (uric acid crystals building up in the body): 7 people, 43.75%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 43.75%
Fungal Infection: 7 people, 43.75%
Fracture Nonunion (permanent failure of healing following a broken bone): 7 people, 43.75%
Ovarian Cysts (fluid filled sacs of the ovary): 7 people, 43.75%
Foot Fracture: 7 people, 43.75%
Patellofemoral Pain Syndrome (pain in the front of the knee): 7 people, 43.75%
Low Turnover Osteopathy (slow removal of old bone and its replacement by new bone): 7 people, 43.75%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 43.75%
Headache (pain in head): 7 people, 43.75%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 18.75%
Swelling: 2 people, 12.50%
Pain: 2 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 12.50%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 12.50%
Immunodeficiency Common Variable: 2 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
Sleep Disorder: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and have Rectal prolapse?

- Check whether Rectal prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sumatriptan:

Sumatriptan (18,159 reports)

Rectal prolapse treatments and more:

Rectal prolapse (1,711 reports)

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal prolapse:

Rectal prolapse (309 drugs)

Browse all the conditions that are associated with Rectal prolapse:

Rectal prolapse (341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate (the active ingredients of Sumatriptan) and Sumatriptan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.