Suprane and Bradycardia - a phase IV clinical study of FDA data

Summary:

Bradycardia is reported as a side effect among people who take Suprane (desflurane), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Propofol, and have General anaesthesia.

The phase IV clinical study analyzes which people have Bradycardia when taking Suprane. It is created by eHealthMe based on reports of 1,000 people who have side effects when taking Suprane from the FDA, and is updated regularly.

What is Suprane?

Suprane has active ingredients of desflurane. eHealthMe is studying from 1,000 Suprane users. Check the latest studies of Suprane.

What is Bradycardia?

Bradycardia (abnormally slow heart action) is found to be associated with 1,916 drugs and 3,118 conditions by eHealthMe. Check the latest studies of Bradycardia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

1,000 people reported to have side effects when taking Suprane.
Among them, 52 people (5.2%) have Bradycardia.

Could Suprane cause Bradycardia?

Among these 52 people:

How long have people been on Suprane when they have Bradycardia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bradycardia when taking Suprane? *

  • female: 57.14 %
  • male: 42.86 %

What is the age of people who have Bradycardia when taking Suprane? *

  • 0-1: 0.0 %
  • 2-9: 7.41 %
  • 10-19: 11.11 %
  • 20-29: 7.41 %
  • 30-39: 7.41 %
  • 40-49: 7.41 %
  • 50-59: 11.11 %
  • 60+: 48.15 %

What are other drugs people take besides Suprane? *

  1. Propofol: 10 people, 19.23%
  2. Fentanyl: 5 people, 9.62%
  3. Cefazolin Sodium: 4 people, 7.69%
  4. Rocuronium Bromide: 4 people, 7.69%
  5. Dexamethasone: 3 people, 5.77%
  6. Midazolam: 3 people, 5.77%
  7. Ondansetron: 3 people, 5.77%
  8. Diprivan: 3 people, 5.77%
  9. Alfentanil: 3 people, 5.77%
  10. Midazolam Hydrochloride: 3 people, 5.77%

What are other side effects people have besides Bradycardia? *

  1. Cardiac Arrest: 14 people, 26.92%
  2. Hypotension (abnormally low blood pressure): 5 people, 9.62%
  3. Ventricular Fibrillation (abnormally irregular heart rhythm): 5 people, 9.62%
  4. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 3 people, 5.77%
  5. Electrocardiogram St Segment Depression: 3 people, 5.77%
  6. Pulseless Electrical Activity: 3 people, 5.77%
  7. Disseminated Intravascular Coagulation (systemic activation of blood coagulation): 2 people, 3.85%
  8. Fever: 2 people, 3.85%
  9. Fatigue (feeling of tiredness): 2 people, 3.85%
  10. Encephalopathy (functioning of the brain is affected by some agent or condition): 2 people, 3.85%

What are the existing conditions these people have? *

  1. General Anaesthesia: 33 people, 63.46%
  2. Anaesthesia: 5 people, 9.62%
  3. Sedation: 3 people, 5.77%
  4. Neuromuscular Blockade Reversal: 3 people, 5.77%
  5. Neuromuscular Blockade: 3 people, 5.77%
  6. High Blood Pressure: 3 people, 5.77%
  7. Epidural Anaesthesia: 3 people, 5.77%
  8. Panic Disorder: 2 people, 3.85%
  9. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 3.85%
  10. Gastric Ulcer (stomach ulcer): 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Suprane and have Bradycardia?

- Check whether Bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Suprane:

Bradycardia treatments and more:

How severe was Bradycardia and when was it recovered:

Expand to all the drugs that have ingredients of desflurane:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Suprane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradycardia:

Browse all the conditions that are associated with Bradycardia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on desflurane (the active ingredients of Suprane) and Suprane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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