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Sustiva and Herpes simplex - a phase IV clinical study of FDA data

Summary:

Herpes simplex is reported as a side effect among people who take Sustiva (efavirenz), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Videx, and have Convulsion.

The phase IV clinical study analyzes which people have Herpes simplex when taking Sustiva. It is created by eHealthMe based on reports of 10,977 people who have side effects when taking Sustiva from the FDA, and is updated regularly.

What is Sustiva?

Sustiva has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 11,040 Sustiva users. Check the latest studies of Sustiva.

What is Herpes simplex?

Herpes simplex (herpes simplex is a common viral infection) is found to be associated with 715 drugs and 895 conditions by eHealthMe. Check the latest studies of Herpes simplex.

On Jul, 26, 2026

10,977 people reported to have side effects when taking Sustiva.
Among them, 15 people (0.14%) have Herpes simplex.

Could Sustiva cause Herpes simplex?

Among these 15 people:

How long have people been on Sustiva when they have Herpes simplex? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Herpes simplex when taking Sustiva? *

  • female: 35.71 %
  • male: 64.29 %

What is the age of people who have Herpes simplex when taking Sustiva? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 7.69 %
  • 20-29: 15.38 %
  • 30-39: 15.38 %
  • 40-49: 38.46 %
  • 50-59: 15.38 %
  • 60+: 7.69 %

What are other drugs people take besides Sustiva? *

  1. Videx: 5 people, 33.33%
  2. Zidovudine: 4 people, 26.67%
  3. Zerit: 4 people, 26.67%
  4. Crixivan: 4 people, 26.67%
  5. Epivir: 3 people, 20.00%
  6. Amoxicillin: 2 people, 13.33%
  7. Ziagen: 2 people, 13.33%
  8. Viread: 2 people, 13.33%
  9. Norvir: 2 people, 13.33%
  10. Kaletra: 2 people, 13.33%

What are other side effects people have besides Herpes simplex? *

  1. Fever: 6 people, 40.00%
  2. Thrombocytopenia (decrease of platelets in blood): 4 people, 26.67%
  3. Psoriasis (immune-mediated disease that affects the skin): 4 people, 26.67%
  4. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 26.67%
  5. Diabetes Mellitus Aggravated (serious diabetes): 3 people, 20.00%
  6. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 13.33%
  7. Cough: 2 people, 13.33%
  8. Diarrhea: 2 people, 13.33%
  9. Drug Resistance (reduction in effectiveness of a drug): 2 people, 13.33%
  10. Erection Problems: 2 people, 13.33%

What are the existing conditions these people have? *

  1. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 6.67%
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sustiva and have Herpes simplex?

- Check whether Herpes simplex is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sustiva:

Herpes simplex treatments and more:

How severe was Herpes simplex and when was it recovered:

Expand to all the drugs that have ingredients of efavirenz:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sustiva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes simplex:

Browse all the conditions that are associated with Herpes simplex:

How the study uses the data?

The study uses data from the FDA. It is based on efavirenz (the active ingredients of Sustiva) and Sustiva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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