Sustiva and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Sustiva (efavirenz), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Truvada, and have Acquired immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Sustiva. It is created by eHealthMe based on reports of 10,977 people who have side effects when taking Sustiva from the FDA, and is updated regularly.

What is Sustiva?

Sustiva has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 11,040 Sustiva users. Check the latest studies of Sustiva.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 857 drugs and 1,062 conditions by eHealthMe. Check the latest studies of Hip joint replacement.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

10,977 people reported to have side effects when taking Sustiva.
Among them, 31 people (0.28%) have Hip joint replacement.

Could Sustiva cause Hip joint replacement?

Among these 31 people:

How long have people been on Sustiva when they have Hip joint replacement? *

What is the gender of people who have Hip joint replacement when taking Sustiva? *

female: 19.35 %
male: 80.65 %

What is the age of people who have Hip joint replacement when taking Sustiva? *

What are other drugs people take besides Sustiva? *

What are other side effects people have besides Hip joint replacement? *

Pain: 28 people, 90.32%
Emotional Distress: 28 people, 90.32%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 24 people, 77.42%
Stress And Anxiety: 24 people, 77.42%
Bone Density Decreased: 22 people, 70.97%
Osteoporosis (bones weak and more likely to break): 20 people, 64.52%
Bone Loss: 18 people, 58.06%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 17 people, 54.84%
Chronic Kidney Disease: 16 people, 51.61%
Osteopenia (a condition where bone mineral density is lower than normal): 16 people, 51.61%

What are the existing conditions these people have? *

Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 5 people, 16.13%
Pneumonia: 1 person, 3.23%
Nausea (feeling of having an urge to vomit): 1 person, 3.23%
Herpes Zoster: 1 person, 3.23%
Hepatitis C: 1 person, 3.23%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Sustiva and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Sustiva:

Sustiva (11,040 reports)

Browse all side effects of Sustiva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Hip joint replacement (857 drugs)

Browse all the conditions that are associated with Hip joint replacement:

Hip joint replacement (1,062 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on efavirenz (the active ingredients of Sustiva) and Sustiva (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.