Symbicort and Hypophysitis - a phase IV clinical study of FDA data

Summary:

Hypophysitis is reported as a side effect among people who take Symbicort (budesonide; formoterol fumarate dihydrate), especially for people who are male, 60+ old, also take Opdivo, and have Malignant melanoma.

The phase IV clinical study analyzes which people have Hypophysitis when taking Symbicort. It is created by eHealthMe based on reports of 112,650 people who have side effects when taking Symbicort from the FDA, and is updated regularly.

What is Symbicort?

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.

What is Hypophysitis?

Hypophysitis (inflammation of the pituitary gland) is found to be associated with 155 drugs and 173 conditions by eHealthMe. Check the latest studies of Hypophysitis.

On Jul, 15, 2026

112,650 people reported to have side effects when taking Symbicort.
Among them, 16 people (0.01%) have Hypophysitis.

Among these 16 people:

What is the gender of people who have Hypophysitis when taking Symbicort? *

female: 31.25 %
male: 68.75 %

What is the age of people who have Hypophysitis when taking Symbicort? *

What are other drugs people take besides Symbicort? *

What are other side effects people have besides Hypophysitis? *

Altered State Of Consciousness (altered state of mind): 6 people, 37.50%
Interstitial Nephritis (inflammation of the kidney): 6 people, 37.50%
Hepatic Function Abnormal: 6 people, 37.50%
Fever: 6 people, 37.50%
Metastases To Liver (cancer spreads to liver): 4 people, 25.00%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 25.00%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 18.75%
Primary Hypothyroidism (failure of the thyroid gland to produce or release thyroid hormones into the bloodstream): 3 people, 18.75%
Neuropathy Peripheral (surface nerve damage): 3 people, 18.75%
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 3 people, 18.75%

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 10 people, 62.50%
Pain: 3 people, 18.75%
Metastasis (spreadable cancer to other organ from origin): 3 people, 18.75%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 18.75%
Total Lung Capacity Decreased: 1 person, 6.25%
Non-Small Cell Lung Cancer Stage Iv: 1 person, 6.25%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 6.25%
Neuralgia (pain in one or more nerves): 1 person, 6.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.25%
Dyspnea (difficult or laboured breathing): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Symbicort and have Hypophysitis?

- Check whether Hypophysitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symbicort:

Symbicort (114,792 reports)

Hypophysitis treatments and more:

Hypophysitis (2,640 reports)

How severe was Hypophysitis and when was it recovered:

Hypophysitis in Symbicort

Expand to all the drugs that have ingredients of budesonide; formoterol fumarate dihydrate:

Hypophysitis and drugs with ingredients of budesonide; formoterol fumarate dihydrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophysitis:

Hypophysitis (155 drugs)

Browse all the conditions that are associated with Hypophysitis:

Hypophysitis (173 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate (the active ingredients of Symbicort) and Symbicort (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.