Symbicort and Polyarthritis - a phase IV clinical study of FDA data
Summary:
Polyarthritis is reported as a side effect among people who take Symbicort (budesonide; formoterol fumarate dihydrate), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Spiriva, and have High blood pressure.
The phase IV clinical study analyzes which people have Polyarthritis when taking Symbicort. It is created by eHealthMe based on reports of 112,650 people who have side effects when taking Symbicort from the FDA, and is updated regularly.
What is Symbicort?
Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.
What is Polyarthritis?
Polyarthritis (arthritis which involves 5 or more joints simultaneously) is found to be associated with 492 drugs and 576 conditions by eHealthMe. Check the latest studies of Polyarthritis.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
112,650 people reported to have side effects when taking Symbicort.
Among them, 48 people (0.04%) have Polyarthritis.

Among these 48 people:
How long have people been on Symbicort when they have Polyarthritis? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 100 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Polyarthritis when taking Symbicort? *
- female: 53.19 %
- male: 46.81 %
What is the age of people who have Polyarthritis when taking Symbicort? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 3.03 %
- 20-29: 3.03 %
- 30-39: 57.58 %
- 40-49: 6.06 %
- 50-59: 0.0 %
- 60+: 30.3 %
What are other drugs people take besides Symbicort? *
- Spiriva: 21 people, 43.75%
- Singulair: 18 people, 37.50%
- Flovent: 14 people, 29.17%
- Albuterol Sulfate: 11 people, 22.92%
- Esomeprazole Magnesium: 11 people, 22.92%
- Lyrica: 10 people, 20.83%
- Jardiance: 10 people, 20.83%
- Ibuprofen: 10 people, 20.83%
- Axiron: 9 people, 18.75%
- Metformin Hydrochloride: 9 people, 18.75%
What are other side effects people have besides Polyarthritis? *
- Fall: 19 people, 39.58%
- Joint Pain: 17 people, 35.42%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 17 people, 35.42%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 35.42%
- Pneumonia: 16 people, 33.33%
- Angle Closure Glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity): 15 people, 31.25%
- Bipolar Disorder (mood disorder): 15 people, 31.25%
- Joint Injury: 15 people, 31.25%
- Fatigue (feeling of tiredness): 15 people, 31.25%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 15 people, 31.25%
What are the existing conditions these people have? *
- Type 2 Diabetes: 9 people, 18.75%
- High Blood Pressure: 9 people, 18.75%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 10.42%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.25%
- Pain: 3 people, 6.25%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 4.17%
- Hypersensitivity: 2 people, 4.17%
- Diabetes: 2 people, 4.17%
- Rashes (redness): 2 people, 4.17%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Symbicort and have Polyarthritis?
- Check whether Polyarthritis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Symbicort:
- Symbicort (114,792 reports)
Polyarthritis treatments and more:
- Polyarthritis (13,132 reports)
How severe was Polyarthritis and when was it recovered:
Expand to all the drugs that have ingredients of budesonide; formoterol fumarate dihydrate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Symbicort:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Polyarthritis:
- Polyarthritis (492 drugs)
Browse all the conditions that are associated with Polyarthritis:
- Polyarthritis (576 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate (the active ingredients of Symbicort) and Symbicort (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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