Symbicort and Tryptase increased - a phase IV clinical study of FDA data

Summary:

Tryptase increased is reported as a side effect among people who take Symbicort (budesonide; formoterol fumarate dihydrate), especially for people who are male, 60+ old, also take Nucala, and have Chronic thyroiditis.

The phase IV clinical study analyzes which people have Tryptase increased when taking Symbicort. It is created by eHealthMe based on reports of 112,650 people who have side effects when taking Symbicort from the FDA, and is updated regularly.

What is Symbicort?

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.

What is Tryptase increased?

Tryptase increased is found to be associated with 72 drugs and 123 conditions by eHealthMe. Check the latest studies of Tryptase increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

112,650 people reported to have side effects when taking Symbicort.
Among them, 15 people (0.01%) have Tryptase increased.

Could Symbicort cause Tryptase increased?

Among these 15 people:

What is the gender of people who have Tryptase increased when taking Symbicort? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Tryptase increased when taking Symbicort? *

What are other drugs people take besides Symbicort? *

What are other side effects people have besides Tryptase increased? *

Blood Immunoglobulin E Increased: 13 people, 86.67%
Wheezing (a high-pitched whistling sound made while you breath): 9 people, 60.00%
Dyspnea (difficult or laboured breathing): 9 people, 60.00%
Infection: 9 people, 60.00%
Fungal Infection: 9 people, 60.00%
Middle Ear Effusion (fluid in middle ear): 9 people, 60.00%
Multiple Allergies (allergy to multiple agents): 9 people, 60.00%
Nasal Disorder (diseases of nose): 9 people, 60.00%
Nasal Mucosal Disorder (disease of mucous membrane): 9 people, 60.00%
Nasal Obstruction (blockage of nose): 9 people, 60.00%

What are the existing conditions these people have? *

Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 33.33%
Type 1 Diabetes: 5 people, 33.33%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 5 people, 33.33%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 6.67%
Hypersensitivity: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Symbicort and have Tryptase increased?

- Check whether Tryptase increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symbicort:

Symbicort (114,792 reports)

Tryptase increased treatments and more:

Tryptase increased (634 reports)

How severe was Tryptase increased and when was it recovered:

Tryptase increased in Symbicort

Expand to all the drugs that have ingredients of budesonide; formoterol fumarate dihydrate:

Tryptase increased and drugs with ingredients of budesonide; formoterol fumarate dihydrate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tryptase increased:

Tryptase increased (72 drugs)

Browse all the conditions that are associated with Tryptase increased:

Tryptase increased (123 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate (the active ingredients of Symbicort) and Symbicort (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.