Symbyax and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Symbyax (fluoxetine hydrochloride; olanzapine), especially for people who are male, 50-59 old, have been taking the drug for 1 - 2 years also take Zyprexa, and have Schizophrenia.

The phase IV clinical study analyzes which people have Heart attack when taking Symbyax. It is created by eHealthMe based on reports of 1,347 people who have side effects when taking Symbyax from the FDA, and is updated regularly.

What is Symbyax?

Symbyax has active ingredients of fluoxetine hydrochloride; olanzapine. It is often used in depression. eHealthMe is studying from 1,449 Symbyax users. Check the latest studies of Symbyax.

What is Heart attack?

Heart attack is found to be associated with 2,474 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

1,347 people reported to have side effects when taking Symbyax.
Among them, 20 people (1.48%) have Heart attack.

Could Symbyax cause Heart attack?

Among these 20 people:

How long have people been on Symbyax when they have Heart attack? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart attack when taking Symbyax? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Heart attack when taking Symbyax? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.25 %
  • 40-49: 25.0 %
  • 50-59: 43.75 %
  • 60+: 25.0 %

What are other drugs people take besides Symbyax? *

  1. Zyprexa: 8 people, 40.00%
  2. Seroquel: 4 people, 20.00%
  3. Zantac: 3 people, 15.00%
  4. Celexa: 2 people, 10.00%
  5. Furosemide: 2 people, 10.00%
  6. Zoloft: 2 people, 10.00%
  7. Metoprolol Tartrate: 2 people, 10.00%
  8. Norvasc: 2 people, 10.00%
  9. Roxicet: 2 people, 10.00%
  10. Abilify: 2 people, 10.00%

What are other side effects people have besides Heart attack? *

  1. Diabetes: 9 people, 45.00%
  2. High Blood Cholesterol: 5 people, 25.00%
  3. Fatigue (feeling of tiredness): 4 people, 20.00%
  4. Type 2 Diabetes: 4 people, 20.00%
  5. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 20.00%
  6. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 15.00%
  7. Acute Kidney Failure: 2 people, 10.00%
  8. Productive Cough: 2 people, 10.00%
  9. Weight Increased: 2 people, 10.00%
  10. High Blood Pressure: 2 people, 10.00%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 15.00%
  2. Stress And Anxiety: 2 people, 10.00%
  3. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 5.00%
  4. Headache (pain in head): 1 person, 5.00%
  5. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 5.00%
  6. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 1 person, 5.00%
  7. Back Pain: 1 person, 5.00%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Symbyax and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symbyax:

Heart attack treatments and more:

How severe was Heart attack and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride; olanzapine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbyax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Browse all the conditions that are associated with Heart attack:


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride; olanzapine (the active ingredients of Symbyax) and Symbyax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: