Tacrolimus and Hepatitis b surface antigen positive - a phase IV clinical study of FDA data

Summary:

Hepatitis b surface antigen positive is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Sofosbuvir, and have Chronic myeloid leukaemia.

The phase IV clinical study analyzes which people have Hepatitis b surface antigen positive when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,161 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Hepatitis b surface antigen positive?

Hepatitis b surface antigen positive is found to be associated with 39 drugs and 185 conditions by eHealthMe. Check the latest studies of Hepatitis b surface antigen positive.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 11 people (0.01%) have Hepatitis b surface antigen positive.

Could Tacrolimus cause Hepatitis b surface antigen positive?

Among these 11 people:

How long have people been on Tacrolimus when they have Hepatitis b surface antigen positive? *

What is the gender of people who have Hepatitis b surface antigen positive when taking Tacrolimus? *

female: 18.18 %
male: 81.82 %

What is the age of people who have Hepatitis b surface antigen positive when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

Sofosbuvir: 6 people, 54.55%
Ranitidine Hydrochloride: 2 people, 18.18%
Prednisone: 2 people, 18.18%
Omeprazole: 2 people, 18.18%
Nystatin: 2 people, 18.18%
Mycophenolate Mofetil: 2 people, 18.18%
Fluconazole: 2 people, 18.18%
Bisoprolol Fumarate: 2 people, 18.18%
Acyclovir: 2 people, 18.18%
Sirolimus: 1 person, 9.09%

What are other side effects people have besides Hepatitis b surface antigen positive? *

Hepatic Enzyme Increased: 6 people, 54.55%
Nodular Regenerative Hyperplasia (regeneration of a skin condition characterized by crops of small, tender, erythematous nodules on the legs): 4 people, 36.36%
Hepatic Fibrosis (scarring process that represents the liver's response to injury): 4 people, 36.36%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 27.27%
Hepatitis B E Antigen Positive: 3 people, 27.27%
Urinary Tract Infection: 2 people, 18.18%
Pneumonia: 2 people, 18.18%
Dehydration (dryness resulting from the removal of water): 2 people, 18.18%
Diarrhea: 2 people, 18.18%
Herpes Virus Infection: 2 people, 18.18%

What are the existing conditions these people have? *

Transplant Rejection (a transplant material is not worked): 1 person, 9.09%
Immunodeficiency Disorders: 1 person, 9.09%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 9.09%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Hepatitis b surface antigen positive?

- Check whether Hepatitis b surface antigen positive is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,161 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis b surface antigen positive:

Hepatitis b surface antigen positive (39 drugs)

Browse all the conditions that are associated with Hepatitis b surface antigen positive:

Hepatitis b surface antigen positive (185 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.