Tacrolimus and Hypophosphataemia - a phase IV clinical study of FDA data

Summary:

Hypophosphataemia is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Mycophenolic Acid, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Hypophosphataemia when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Hypophosphataemia?

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood) is found to be associated with 869 drugs and 782 conditions by eHealthMe. Check the latest studies of Hypophosphataemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 77 people (0.07%) have Hypophosphataemia.

Could Tacrolimus cause Hypophosphataemia?

Among these 77 people:

How long have people been on Tacrolimus when they have Hypophosphataemia? *

What is the gender of people who have Hypophosphataemia when taking Tacrolimus? *

female: 56.72 %
male: 43.28 %

What is the age of people who have Hypophosphataemia when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

What are other side effects people have besides Hypophosphataemia? *

Acute Kidney Failure: 18 people, 23.38%
Diarrhea: 18 people, 23.38%
Weakness: 17 people, 22.08%
Osteomalacia (softening of the bones due to a lack of vitamin d): 15 people, 19.48%
Anaemia (lack of blood): 14 people, 18.18%
Cytomegalovirus Infection: 14 people, 18.18%
Hypokalemia (low potassium): 14 people, 18.18%
Joint Pain: 13 people, 16.88%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 13 people, 16.88%
Nausea (feeling of having an urge to vomit): 12 people, 15.58%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 24 people, 31.17%
Hepatitis B: 9 people, 11.69%
Cytomegalovirus Infection: 6 people, 7.79%
Osteoporosis (bones weak and more likely to break): 6 people, 7.79%
High Blood Pressure: 5 people, 6.49%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 5.19%
Pain: 4 people, 5.19%
Iron Deficiency Anaemia: 4 people, 5.19%
Fever: 3 people, 3.90%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 3.90%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Hypophosphataemia?

- Check whether Hypophosphataemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,160 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophosphataemia:

Hypophosphataemia (869 drugs)

Browse all the conditions that are associated with Hypophosphataemia:

Hypophosphataemia (782 conditions)

Related publications that referenced our studies

Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.