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Tacrolimus and Retinal detachment - a phase IV clinical study of FDA data

Summary:

Retinal detachment is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 50-59 old, have been taking the drug for 1 - 6 months also take Prednisolone, and have Cytomegalovirus viraemia.

The phase IV clinical study analyzes which people have Retinal detachment when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Retinal detachment?

Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue) is found to be associated with 714 drugs and 1,007 conditions by eHealthMe. Check the latest studies of Retinal detachment.

On Jul, 15, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 74 people (0.06%) have Retinal detachment.

Could Tacrolimus cause Retinal detachment?

Among these 74 people:

How long have people been on Tacrolimus when they have Retinal detachment? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Retinal detachment when taking Tacrolimus? *

  • female: 28.12 %
  • male: 71.88 %

What is the age of people who have Retinal detachment when taking Tacrolimus? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.45 %
  • 20-29: 6.9 %
  • 30-39: 0.0 %
  • 40-49: 10.34 %
  • 50-59: 43.1 %
  • 60+: 36.21 %

What are other drugs people take besides Tacrolimus? *

  1. Methylprednisolone: 14 people, 18.92%
  2. Prednisolone: 14 people, 18.92%
  3. Ciclosporin: 13 people, 17.57%
  4. Mycophenolate Mofetil: 10 people, 13.51%
  5. Ganciclovir: 10 people, 13.51%
  6. Cyclosporine: 8 people, 10.81%
  7. Sirolimus: 7 people, 9.46%
  8. Leflunomide: 7 people, 9.46%
  9. Azathioprine: 7 people, 9.46%
  10. Cytotec: 5 people, 6.76%

What are other side effects people have besides Retinal detachment? *

  1. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 31 people, 41.89%
  2. Visual Impairment: 23 people, 31.08%
  3. Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 22 people, 29.73%
  4. Drug Resistance (reduction in effectiveness of a drug): 22 people, 29.73%
  5. Retinal Scar (development of scar tissue on retina): 19 people, 25.68%
  6. Nephropathy Toxic (damage to kidney due to toxins): 19 people, 25.68%
  7. Renal Impairment (severely reduced kidney function): 19 people, 25.68%
  8. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 19 people, 25.68%
  9. Vitreous Haemorrhage (intraocular (inside the eye) bleeding): 8 people, 10.81%
  10. Rashes (redness): 8 people, 10.81%

What are the existing conditions these people have? *

  1. Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 22 people, 29.73%
  2. Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 22 people, 29.73%
  3. Immunodeficiency Disorders: 20 people, 27.03%
  4. High Blood Pressure: 6 people, 8.11%
  5. Transplant Rejection (a transplant material is not worked): 4 people, 5.41%
  6. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 5.41%
  7. Rosacea (a skin condition that causes facial redness): 3 people, 4.05%
  8. Pneumonia Cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 3 people, 4.05%
  9. Lichen Sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain): 3 people, 4.05%
  10. Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 3 people, 4.05%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Retinal detachment?

- Check whether Retinal detachment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Retinal detachment treatments and more:

How severe was Retinal detachment and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinal detachment:

Browse all the conditions that are associated with Retinal detachment:

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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