Tacrolimus and Retinal ischaemia - a phase IV clinical study of FDA data

Summary:

Retinal ischaemia is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 30-39 old, also take Posaconazole, and have Graft versus host disease in skin.

The phase IV clinical study analyzes which people have Retinal ischaemia when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Retinal ischaemia?

Retinal ischaemia (lack of blood supply to retina) is found to be associated with 115 drugs and 188 conditions by eHealthMe. Check the latest studies of Retinal ischaemia.

On Jul, 12, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 27 people (0.02%) have Retinal ischaemia.

Could Tacrolimus cause Retinal ischaemia?

Among these 27 people:

What is the gender of people who have Retinal ischaemia when taking Tacrolimus? *

female: 16 %
male: 84 %

What is the age of people who have Retinal ischaemia when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

Posaconazole: 18 people, 66.67%
Insulin: 14 people, 51.85%
Prednisone: 5 people, 18.52%
Sulfamethoxazole And Trimethoprim: 4 people, 14.81%
Mycophenolate Mofetil: 3 people, 11.11%
Voriconazole: 2 people, 7.41%
Omeprazole: 2 people, 7.41%
Loperamide Hydrochloride: 2 people, 7.41%
Budesonide: 2 people, 7.41%
Amphotericin B: 2 people, 7.41%

What are other side effects people have besides Retinal ischaemia? *

Retinal Haemorrhage (bleeding from retina): 22 people, 81.48%
Necrotising Retinitis (life threatening infection of retina): 18 people, 66.67%
Eye Infection Fungal: 18 people, 66.67%
Septic Embolus (a type of embolism that is infected with bacteria): 18 people, 66.67%
Cerebral Artery Embolism (sudden blocking of an artery by a clot or foreign material): 18 people, 66.67%
Cerebral Aspergillosis (pus collection with swelling in brain): 18 people, 66.67%
Cerebral Haematoma (collection of blood in brain): 18 people, 66.67%
Cerebral Haemorrhage (bleeding within the brain): 18 people, 66.67%
Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 17 people, 62.96%
Drug Ineffective: 15 people, 55.56%

What are the existing conditions these people have? *

Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 15 people, 55.56%
Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 14 people, 51.85%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 7 people, 25.93%
Retinitis Viral (viral infection of retina): 4 people, 14.81%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 2 people, 7.41%
Pneumonia: 2 people, 7.41%
Chronic Graft Versus Host Disease In Skin (damage by immune cells to skin after grafting): 2 people, 7.41%
Acute Graft Versus Host Disease In Skin (acute complication on skin following an allogeneic tissue/blood transplant): 2 people, 7.41%
Immunosuppressant Drug Level: 1 person, 3.70%
Immunodeficiency Disorders: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Retinal ischaemia?

- Check whether Retinal ischaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,160 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinal ischaemia:

Retinal ischaemia (115 drugs)

Browse all the conditions that are associated with Retinal ischaemia:

Retinal ischaemia (188 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.