Tacrolimus and Ureteric obstruction - a phase IV clinical study of FDA data

Summary:

Ureteric obstruction is reported as a side effect among people who take Tacrolimus (tacrolimus), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methylprednisolone, and have Immunodeficiency disorders.

The phase IV clinical study analyzes which people have Ureteric obstruction when taking Tacrolimus. It is created by eHealthMe based on reports of 115,828 people who have side effects when taking Tacrolimus from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,161 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Ureteric obstruction?

Ureteric obstruction is found to be associated with 348 drugs and 362 conditions by eHealthMe. Check the latest studies of Ureteric obstruction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

115,828 people reported to have side effects when taking Tacrolimus.
Among them, 55 people (0.05%) have Ureteric obstruction.

Could Tacrolimus cause Ureteric obstruction?

Among these 55 people:

How long have people been on Tacrolimus when they have Ureteric obstruction? *

What is the gender of people who have Ureteric obstruction when taking Tacrolimus? *

female: 41.51 %
male: 58.49 %

What is the age of people who have Ureteric obstruction when taking Tacrolimus? *

What are other drugs people take besides Tacrolimus? *

Methylprednisolone: 26 people, 47.27%
Azathioprine: 21 people, 38.18%
Mycophenolate Mofetil: 20 people, 36.36%
Prednisolone: 11 people, 20.00%
Fluconazole: 10 people, 18.18%
Cyclosporine: 10 people, 18.18%
Simulect: 8 people, 14.55%
Prednisone: 7 people, 12.73%
Myfortic: 7 people, 12.73%
Omeprazole: 6 people, 10.91%

What are other side effects people have besides Ureteric obstruction? *

Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 24 people, 43.64%
Fever: 14 people, 25.45%
Blood Creatinine Increased: 11 people, 20.00%
Polyomavirus-Associated Nephropathy (polyomavirus-associated kidney disease): 10 people, 18.18%
Complications Of Transplanted Kidney: 10 people, 18.18%
Septic Shock (shock due to blood infection): 10 people, 18.18%
Anaemia (lack of blood): 9 people, 16.36%
Strabismus (a disorder in which the two eyes do not line up in the same direction): 9 people, 16.36%
Leukopenia (less number of white blood cells in blood): 7 people, 12.73%
Kidney Transplant Rejection: 7 people, 12.73%

What are the existing conditions these people have? *

Immunodeficiency Disorders: 18 people, 32.73%
Transplant Rejection (a transplant material is not worked): 10 people, 18.18%
Cytomegalovirus Infection: 8 people, 14.55%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 6 people, 10.91%
Fungal Peritonitis (fungal infection silk like membrane lines inner abdominal wall): 6 people, 10.91%
Candidiasis (candidiasis or thrush is a fungal infection): 5 people, 9.09%
Diarrhea: 4 people, 7.27%
Kidney Transplant Rejection: 4 people, 7.27%
Infection: 4 people, 7.27%
Urination - Excessive Volume: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Tacrolimus and have Ureteric obstruction?

- Check whether Ureteric obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tacrolimus:

Tacrolimus (116,161 reports)

Browse all side effects of Tacrolimus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ureteric obstruction:

Ureteric obstruction (348 drugs)

Browse all the conditions that are associated with Ureteric obstruction:

Ureteric obstruction (362 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Tacrolimus) and Tacrolimus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.