Tadalafil and Haemodynamic instability - a phase IV clinical study of FDA data

Summary:

Haemodynamic instability is reported as a side effect among people who take Tadalafil (tadalafil), especially for people who are female, 40-49 old, also take Ambrisentan, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Haemodynamic instability when taking Tadalafil. It is created by eHealthMe based on reports of 25,126 people who have side effects when taking Tadalafil from the FDA, and is updated regularly.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,549 Tadalafil users. Check the latest studies of Tadalafil.

What is Haemodynamic instability?

Haemodynamic instability (disturbances in the blood movement in our body) is found to be associated with 550 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Haemodynamic instability.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

25,126 people reported to have side effects when taking Tadalafil.
Among them, 25 people (0.1%) have Haemodynamic instability.

Could Tadalafil cause Haemodynamic instability?

Among these 25 people:

What is the gender of people who have Haemodynamic instability when taking Tadalafil? *

female: 85 %
male: 15 %

What is the age of people who have Haemodynamic instability when taking Tadalafil? *

What are other drugs people take besides Tadalafil? *

What are other side effects people have besides Haemodynamic instability? *

Headache (pain in head): 9 people, 36.00%
Dyspnea (difficult or laboured breathing): 8 people, 32.00%
Hypotension (abnormally low blood pressure): 7 people, 28.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 24.00%
Skin Blushing/flushing (a sudden reddening of the face, neck): 4 people, 16.00%
Catheter Site Haemorrhage (bleeding at catheter site): 3 people, 12.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 12.00%
Pulmonary Hypertensive Crisis (increase in blood pressure in the lung artery-crisis): 3 people, 12.00%
Right Ventricular Failure (right half of the heart fails to work): 3 people, 12.00%
Pulmonary Arterial Pressure Increased: 3 people, 12.00%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 19 people, 76.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 12.00%
Portopulmonary Hypertension (coexistence of portal and pulmonary hypertension): 1 person, 4.00%
Maternal Therapy To Enhance Foetal Lung Maturity: 1 person, 4.00%
Loeffler's Syndrome (a condition that causes the lungs to become inflamed with increased no. of eosinophilia in blood): 1 person, 4.00%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 4.00%
Hypercoagulation (increased tendency for clotting of the blood): 1 person, 4.00%
Headache (pain in head): 1 person, 4.00%
Cardiac Failure: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Tadalafil and have Haemodynamic instability?

- Check whether Haemodynamic instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Tadalafil:

Tadalafil (25,549 reports)

Browse all side effects of Tadalafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemodynamic instability:

Haemodynamic instability (550 drugs)

Browse all the conditions that are associated with Haemodynamic instability:

Haemodynamic instability (1,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil (the active ingredients of Tadalafil) and Tadalafil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.