Talwin and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Talwin (pentazocine lactate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Vioxx, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Constipation when taking Talwin. It is created by eHealthMe based on reports of 870 people who have side effects when taking Talwin from the FDA, and is updated regularly.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,619 conditions by eHealthMe. Check the latest studies of Constipation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

870 people reported to have side effects when taking Talwin.
Among them, 14 people (1.61%) have Constipation.

Among these 14 people:

How long have people been on Talwin when they have Constipation? *

What is the gender of people who have Constipation when taking Talwin? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Constipation when taking Talwin? *

What are other drugs people take besides Talwin? *

What are other side effects people have besides Constipation? *

Joint Pain: 4 people, 28.57%
Abdominal Pain: 4 people, 28.57%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 21.43%
Emotional Distress: 3 people, 21.43%
Neck Pain: 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Diarrhea: 3 people, 21.43%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 21.43%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 21.43%
Stress And Anxiety: 2 people, 14.29%
Joint Pain: 2 people, 14.29%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
High Blood Cholesterol: 2 people, 14.29%
High Blood Pressure: 2 people, 14.29%
Osteoporosis (bones weak and more likely to break): 2 people, 14.29%
Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 2 people, 14.29%
Migraine (headache): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Talwin and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Talwin:

Talwin (893 reports)

Constipation treatments and more:

Constipation (337,881 reports)

Browse all side effects of Talwin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,619 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pentazocine lactate (the active ingredients of Talwin) and Talwin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.