Talwin and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Talwin (pentazocine lactate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Vioxx, and have High blood pressure.

The phase IV clinical study analyzes which people have Heart attack when taking Talwin. It is created by eHealthMe based on reports of 870 people who have side effects when taking Talwin from the FDA, and is updated regularly.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.

What is Heart attack?

Heart attack is found to be associated with 2,475 drugs and 3,298 conditions by eHealthMe. Check the latest studies of Heart attack.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 09, 2026

870 people reported to have side effects when taking Talwin.
Among them, 15 people (1.72%) have Heart attack.

Could Talwin cause Heart attack?

Among these 15 people:

How long have people been on Talwin when they have Heart attack? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart attack when taking Talwin? *

  • female: 20 %
  • male: 80 %

What is the age of people who have Heart attack when taking Talwin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 78.57 %
  • 60+: 7.14 %

What are other drugs people take besides Talwin? *

  1. Valium: 12 people, 80.00%
  2. Vioxx: 12 people, 80.00%
  3. Lortab: 11 people, 73.33%
  4. Ultram: 11 people, 73.33%
  5. Ziac: 10 people, 66.67%
  6. Lipitor: 10 people, 66.67%
  7. Buspar: 10 people, 66.67%
  8. Skelaxin: 10 people, 66.67%
  9. Vicodin: 10 people, 66.67%
  10. Claritin: 9 people, 60.00%

What are other side effects people have besides Heart attack? *

  1. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 13 people, 86.67%
  2. High Blood Pressure: 13 people, 86.67%
  3. Cardiac Arrest: 10 people, 66.67%
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 66.67%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 66.67%
  6. Chest Pain: 10 people, 66.67%
  7. Stable Angina (a constant chest pain): 9 people, 60.00%
  8. Intervertebral Disc Protrusion (spinal disc protrusion): 8 people, 53.33%
  9. Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 8 people, 53.33%
  10. High Blood Cholesterol: 8 people, 53.33%

What are the existing conditions these people have? *

  1. Pain In Extremity: 10 people, 66.67%
  2. High Blood Pressure: 10 people, 66.67%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
  4. Stress And Anxiety: 1 person, 6.67%
  5. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 6.67%
  6. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 6.67%
  7. Birth Control: 1 person, 6.67%
  8. Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 1 person, 6.67%
  9. Back Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Talwin and have Heart attack?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Talwin:

Heart attack treatments and more:

How severe was Heart attack and when was it recovered:

Expand to all the drugs that have ingredients of pentazocine lactate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Talwin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Browse all the conditions that are associated with Heart attack:


How the study uses the data?

The study uses data from the FDA. It is based on pentazocine lactate (the active ingredients of Talwin) and Talwin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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